Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 14/20 | 0.57 |
| ▸ | CNR2 | P34972 | 13/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.52 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.52 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10988783 | 0.81 | CNR2 (0.51) | CNR1CNR2NR1I2ADORA3SLC6A3 | |
| SCHEMBL10990917 | 0.79 | CNR1 (0.50) | CNR1CNR2 | |
| SCHEMBL11605812 | 0.78 | CNR1 (0.50) | CNR1CNR2NR1I2ADORA3SLC6A3 | |
| SCHEMBL10365477 | 0.78 | CNR2 (0.62) | CNR1CNR2 | |
| SCHEMBL10989218 | 0.77 | ALDH1A1 (0.60) | CNR1CNR2ALDH1A1 | |
| SCHEMBL31545670 | 0.77 | CNR2 (0.53) | CNR1CNR2NR1I2ADORA3SLC6A3 | |
| SCHEMBL19281379 | 0.76 | CNR1 (0.56) | CNR1CNR2NR1I2ADORA3SLC6A3 | |
| SCHEMBL10367356 | 0.75 | CNR2 (0.47) | CNR1CNR2NR1I2ADORA3SLC6A3 | |
| SCHEMBL11371918 | 0.75 | CNR2 (0.55) | CNR1CNR2NR1I2ADORA3SLC6A3 | |
| SCHEMBL10365457 | 0.74 | CNR2 (0.58) | CNR1CNR2NR1I2ADORA3SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0089781-B1 | BICYCLIC BENZO FUSED COMPOUNDS | PFIZER INC. (US) | 1990-08-08 | — | — | EP | disclosed |
| US-4870084-A | ANALGESICS, ANTIDIARRHEALS | PFIZER INC. (US) | 1989-09-26 | — | — | US | disclosed |
| US-4863934-A | Bicyclic benzo fused pyran compounds used for producing analgesia | PFIZER INC. (US) | 1989-09-05 | — | — | US | disclosed |
| US-4841078-A | ANALGESICS | PFIZER INC. (US) | 1989-06-20 | — | — | US | disclosed |
| US-4680404-A | ANALGESICS, TRANQUILIZERS, ANTIEMETICS, DIURETICS, ANTICONVULSANTS | PFIZER INC. (US) | 1987-07-14 | — | — | US | disclosed |
| US-4486428-A | ANALGESICS, ANTIEMETICS | PFIZER INC. (US) | 1984-12-04 | — | — | US | disclosed |
| EP-0089781-A2 | Bicyclic benzo fused compounds | PFIZER INC. (US) | 1983-09-28 | — | — | EP | disclosed |