Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B3 | P37058 | 7/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.45 |
| ▸ | PLA2G5 | P39877 | 2/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.45 |
| ▸ | CES2 | O00748 | 2/20 | 0.42 |
| ▸ | CES1 | P23141 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | HTR7 | P34969 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28382588 | 0.81 | GSK3B (0.58) | HSD17B3HTTMEN1ALDH1A1MAPT | |
| SCHEMBL12569032 | 0.81 | HSD17B3 (0.49) | HSD17B3HTTMEN1ALDH1A1MAPT | |
| SCHEMBL18048836 | 0.81 | HSD17B3 (0.46) | HSD17B3HTTMEN1ALDH1A1MAPT | |
| SCHEMBL1165071 | 0.79 | GSK3B (0.56) | HSD17B3HTTMEN1ALDH1A1MAPT | |
| SCHEMBL2009655 | 0.79 | GSK3B (0.56) | HSD17B3HTTMEN1ALDH1A1MAPT | |
| SCHEMBL22342723 | 0.78 | HSD17B3 (0.44) | HSD17B3HTTMEN1ALDH1A1MAPT | |
| SCHEMBL21151718 | 0.78 | HSD17B3 (0.47) | HSD17B3HTTMEN1ALDH1A1MAPT | |
| SCHEMBL17955221 | 0.76 | HSD17B3 (0.46) | HSD17B3HTTMEN1ALDH1A1MAPT | |
| SCHEMBL27432330 | 0.75 | GSK3B (0.59) | HSD17B3MEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL12541939 | 0.75 | GSK3B (0.59) | HSD17B3MEN1ALDH1A1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0229660-B1 | NITROGEN-CONTAINING ARYL METHOXYTHIOPHENE DERIVATIVES AND ACID ADDITION SALTS THEREOF, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | CL PHARMA AKTIENGESELLSCHAFT (AT) | 1990-09-26 | — | — | EP | claimed |
| EP-0229660-A2 | Nitrogen-containing aryl methoxythiophene derivatives and acid addition salts thereof, process for their preparation and pharmaceutical compositions containing them | CL PHARMA AKTIENGESELLSCHAFT (AT) | 1987-07-22 | — | — | EP | claimed |
| EP-0229660-B1 | NITROGEN-CONTAINING ARYL METHOXYTHIOPHENE DERIVATIVES AND ACID ADDITION SALTS THEREOF, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | CL PHARMA AKTIENGESELLSCHAFT (AT) | 1990-09-26 | — | — | EP | disclosed |
| US-4778803-A | Nitrogen-arylmethoxy-thiophene derivatives and acid addition salts thereof, and pharmaceutical preparations containing these compounds | CHEMIE LINZ AKTIENGESELLSCHAFT (AT) | 1988-10-18 | — | — | US | disclosed |
| EP-0229660-A2 | Nitrogen-containing aryl methoxythiophene derivatives and acid addition salts thereof, process for their preparation and pharmaceutical compositions containing them | CL PHARMA AKTIENGESELLSCHAFT (AT) | 1987-07-22 | — | — | EP | disclosed |