Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | JAK2 | O60674 | 1/20 | 0.49 |
| ▸ | MITF | O75030 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | ESR1 | P03372 | 1/20 | 0.49 |
| ▸ | CES2 | O00748 | 1/20 | 0.48 |
| ▸ | CES1 | P23141 | 1/20 | 0.48 |
| ▸ | HSD17B3 | P37058 | 6/20 | 0.47 |
| ▸ | DAO | P14920 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2009655 | 1.00 | GSK3B (0.56) | GSK3BKMT2AMAPTNPSR1JAK2 | |
| SCHEMBL12541939 | 0.93 | GSK3B (0.59) | GSK3BKMT2AMAPTNPSR1JAK2 | |
| SCHEMBL5524032 | 0.86 | GSK3B (0.63) | GSK3BKMT2AMAPTNPSR1JAK2 | |
| SCHEMBL6847923 | 0.85 | GSK3B (0.51) | GSK3BKMT2AMAPTNPSR1JAK2 | |
| SCHEMBL15988673 | 0.82 | GSK3B (0.73) | GSK3BKMT2AMAPTNPSR1KDM4E | |
| SCHEMBL6847877 | 0.81 | GSK3B (0.53) | GSK3BKMT2AMAPTNPSR1JAK2 | |
| SCHEMBL6609447 | 0.81 | GSK3B (0.66) | GSK3BKMT2AMAPTNPSR1MITF | |
| SCHEMBL12569032 | 0.81 | HSD17B3 (0.49) | KMT2AMAPTCES2CES1HSD17B3 | |
| SCHEMBL10366015 | 0.79 | HSD17B3 (0.51) | KMT2AMAPTCES2CES1HSD17B3 | |
| SCHEMBL6609187 | 0.79 | GSK3B (0.68) | GSK3BKMT2AMAPTNPSR1MITF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011020712-A2 | OLIGOTHIOPHENES DERIVATIVES | UNIVERSITE LIBRE DE BRUXELLES (BE) | 2011-02-24 | — | — | WO | disclosed |