Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 7/20 | 0.62 |
| ▸ | OPRK1 | P41145 | 7/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10366107 | 1.00 | OPRM1 (0.62) | OPRM1OPRK1 | |
| Hydrochloric Acid SCHEMBL10683355 | 0.99 | OPRM1 (0.64) | OPRM1OPRK1 | |
| SCHEMBL10366721 | 0.85 | OPRM1 (0.66) | OPRM1OPRK1 | |
| SCHEMBL10366719 | 0.85 | OPRM1 (0.66) | OPRM1OPRK1 | |
| Hydrochloric Acid SCHEMBL10670575 | 0.84 | OPRM1 (0.67) | OPRM1OPRK1 | |
| SCHEMBL10367901 | 0.83 | OPRM1 (0.48) | OPRM1OPRK1 | |
| SCHEMBL10367902 | 0.83 | OPRM1 (0.48) | OPRM1OPRK1 | |
| SCHEMBL11049139 | 0.83 | OPRM1 (0.58) | OPRM1OPRK1 | |
| SCHEMBL10367871 | 0.81 | OPRM1 (0.68) | OPRM1OPRK1 | |
| SCHEMBL10366061 | 0.81 | OPRM1 (0.68) | OPRM1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0147085-B1 | SUBSTITUTED TRANS-1.2-DIAMINOCYCLOHEXYL AMIDE COMPOUNDS | WARNER-LAMBERT COMPANY (US) | 1990-03-14 | — | — | EP | claimed |
| EP-0147085-A2 | Substituted trans-1.2-diaminocyclohexyl amide compounds | WARNER-LAMBERT COMPANY (US) | 1985-07-03 | — | — | EP | claimed |
| US-4738981-A | ANALGESICS | WARNER-LAMBERT (US) | 1988-04-19 | — | — | US | disclosed |
| US-4656182-A | ANALGESICS, DIURETICS, PSYCHOTHERAPEUTIC AGENTS | WARNER-LAMBERT COMPANY (US) | 1987-04-07 | — | — | US | disclosed |