Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.61 |
| ▸ | TSHR | P16473 | 2/20 | 0.61 |
| ▸ | BLM | P54132 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | VCP | P55072 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.44 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.43 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HBB | P68871 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | PNP | P00491 | 1/20 | 0.39 |
| ▸ | EDNRA | P25101 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2576527 | 0.87 | MEN1 (0.66) | MEN1KMT2ATSHRBLMALDH1A1 | |
| SCHEMBL14963622 | 0.87 | KMT2A (0.66) | MEN1KMT2ATSHRBLMALDH1A1 | |
| SCHEMBL10364407 | 0.87 | MEN1 (0.61) | MEN1KMT2ATSHRBLMALDH1A1 | |
| SCHEMBL14421454 | 0.84 | MEN1 (0.69) | MEN1KMT2ATSHRBLMALDH1A1 | |
| SCHEMBL14963621 | 0.84 | MEN1 (0.63) | MEN1KMT2ATSHRBLMALDH1A1 | |
| SCHEMBL2467673 | 0.84 | MEN1 (0.71) | MEN1KMT2ATSHRBLMALDH1A1 | |
| SCHEMBL9022143 | 0.82 | KMT2A (0.62) | MEN1KMT2ATSHRBLMALDH1A1 | |
| SCHEMBL8446145 | 0.81 | MEN1 (0.67) | MEN1KMT2ATSHRBLMALDH1A1 | |
| SCHEMBL14421495 | 0.79 | MEN1 (0.70) | MEN1KMT2ATSHRBLMALDH1A1 | |
| SCHEMBL6378699 | 0.79 | MEN1 (0.58) | MEN1KMT2ATSHRBLMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0152965-B1 | PROCESS FOR PREPARING 2,6-SUBSTITUTED-9-(1,3-DIHYDROXY-2-PROPOXY-MENTHYL)-PURINES AND CERTAIN DERIVATIVES | SYNTEX (U.S.A.) INC. (US) | 1990-10-24 | — | — | EP | disclosed |