Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | BPTF | Q12830 | 1/20 | 0.39 |
| ▸ | PDE4A | P27815 | 1/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.37 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 4/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.35 |
| ▸ | PLA2G2D | Q9UNK4 | 1/20 | 0.34 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.34 |
| ▸ | TOP2A | P11388 | 2/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | MRGPRX1 | Q96LB2 | 1/20 | 0.33 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.33 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10366159 | 0.96 | BPTF (0.40) | KDM4ERAB9ASMN1; SMN2BPTFPDE4A | |
| SCHEMBL10368098 | 0.92 | KDM4E (0.43) | KDM4ERAB9ASMN1; SMN2BPTFCNR2 | |
| SCHEMBL10917891 | 0.89 | KDM4E (0.41) | KDM4ERAB9ASMN1; SMN2BPTFPDE4A | |
| SCHEMBL10366274 | 0.88 | KDM4E (0.41) | KDM4ERAB9ASMN1; SMN2BPTFCNR2 | |
| SCHEMBL10366527 | 0.87 | KDM4E (0.39) | KDM4ERAB9ASMN1; SMN2BPTFPDE4A | |
| SCHEMBL10689346 | 0.86 | PPARA (0.34) | BPTFPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL10368185 | 0.86 | PTGER4 (0.41) | KDM4ERAB9ASMN1; SMN2BPTFCNR2 | |
| SCHEMBL10680185 | 0.84 | BPTF (0.40) | KDM4ERAB9ASMN1; SMN2BPTFPDE4A | |
| SCHEMBL10685216 | 0.83 | SMN1; SMN2 (0.41) | KDM4ERAB9ASMN1; SMN2BPTFCNR2 | |
| SCHEMBL10681397 | 0.83 | PLA2G2D (0.41) | MTNR1AMTNR1BPLA2G2DLTB4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0193853-A2 | 3(2H)pyridazinone, process for its preparation and anti-allergic agent containing it | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1986-09-10 | — | — | EP | claimed |
| EP-0193853-B1 | 3(2H)PYRIDAZINONE, PROCESS FOR ITS PREPARATION AND ANTI-ALLERGIC AGENT CONTAINING IT | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1990-09-12 | — | — | EP | disclosed |
| US-4783462-A | 3(2H)pyridazinone, and anti-allergic agent containing it | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1988-11-08 | — | — | US | disclosed |
| EP-0193853-A2 | 3(2H)pyridazinone, process for its preparation and anti-allergic agent containing it | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1986-09-10 | — | — | EP | disclosed |