⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7502622 | 0.57 | — | — | |
| SCHEMBL11390545 | 0.56 | CA1 (0.37) | — | |
| SCHEMBL2001403 | 0.55 | — | — | |
| SCHEMBL11360570 | 0.53 | INMT (0.30) | — | |
| SCHEMBL31261085 | 0.52 | CA1 (0.33) | — | |
| SCHEMBL29589373 | 0.51 | CA1 (0.32) | — | |
| SCHEMBL16661635 | 0.51 | — | — | |
| SCHEMBL8273013 | 0.51 | — | — | |
| SCHEMBL4141702 | 0.50 | — | — | |
| SCHEMBL11688163 | 0.50 | CA1 (0.69) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-5070446-A | — | — | None | — | — | JP | disclosed |
| EP-3440063-A1 | AMINOTHIAZOLE DERIVATIVES USEFUL AS ANTIVIRAL AGENTS | Innovative Molecules GmbH (DE) | 2019-02-13 | — | — | EP | disclosed |
| WO-2018167001-A1 | HETEROCYCLIC COMPOUNDS USEFUL AS DUAL ATX/CA INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2018-09-20 | — | — | WO | disclosed |
| WO-2017174640-A1 | AMINOTHIAZOLE DERIVATIVES USEFUL AS ANTIVIRAL AGENTS | INNOVATIVES MOLECULES GMBH (DE) | 2017-10-12 | — | — | WO | disclosed |
| CN-105377837-A | N-(heteroaryl)-sulfonamide derivatives useful as S100-inhibitors | ACTIVE BIOTECH AB | 2016-03-02 | — | — | CN | disclosed |
| EP-2958921-A1 | PYRROLO [2, 3 -D]PYRIMIDINE DERIVATIVES AS INHIBITORS OF JANUS- RELATED KINASES (JAK) | Pfizer Inc. (US) | 2015-12-30 | — | — | EP | disclosed |
| CN-105008362-A | Pyrrolo [2,3-D ] pyrimidine derivatives as janus-related kinase (JAK) inhibitors | PFIZER | 2015-10-28 | — | — | CN | disclosed |
| CN-102796081-B | Pyrimidine sulphonamide derivatives as chemokine receptor modulators | ASTRAZENECA AB | 2015-04-22 | — | — | CN | disclosed |
| WO-2014128591-A1 | PYRROLO [2, 3 -D]PYRIMIDINE DERIVATIVES AS INHIBITORS OF JANUS- RELATED KINASES (JAK) | PFIZER INC. (US) | 2014-08-28 | — | — | WO | disclosed |
| CN-102083312-B | Benzene sulfonamide thiazole and oxazole compounds | SMITHKLINE BEECHAM CORP | 2014-08-27 | — | — | CN | disclosed |
| US-20020107270-A1 | Heterocyclic aromatic oxazole compounds and use thereof | HARUTA JUNICHI (JP) | 2002-08-08 | — | — | US | disclosed |
| US-20020107271-A1 | Heterocyclic aromatic oxazole compounds and use thereof | HARUTA JUNICHI (JP) | 2002-08-08 | — | — | US | disclosed |
| US-6362209-B1 | ANTIPYRETICS, ANALGESICS, ANTIINFLAMMATORY AGENTS | JAPAN TOBACCO INC. (JP) | 2002-03-26 | — | — | US | disclosed |
| US-6002014-A | SELECTIVELY INHIBITING THE ACTION OF COX-2; TREATING INFLAMMATION | JAPAN TOBACCO, INC. (JP) | 1999-12-14 | — | — | US | disclosed |
| US-5994381-A | ANTIPYRETICS; ANTIINFLAMMATORY AGENTS; ANALGESICS | JAPAN TOBACCO, INC. (JP) | 1999-11-30 | — | — | US | disclosed |
| US-5945539-A | ENZYME INHIBITOR | JAPAN TOBACCO, INC. (JP) | 1999-08-31 | — | — | US | disclosed |
| EP-0745596-B1 | HETEROAROMATIC OXAZOLE COMPOUNDS AND USE THEREOF | JAPAN TOBACCO INC (JP) | 1999-05-19 | — | — | EP | disclosed |
| EP-0826676-A1 | OXAZOLE DERIVATIVES AND USE THEREOF | Japan Tobacco Inc. (JP) | 1998-03-04 | — | — | EP | disclosed |
| EP-0745596-A1 | HETEROAROMATIC OXAZOLE COMPOUNDS AND USE THEREOF | Japan Tobacco Inc. (JP) | 1996-12-04 | — | — | EP | disclosed |
| JP-H0570446-A | N-THIAZOLYLSULFONAMIDE DERIVATIVE | TAISHO PHARMACEUT CO LTD | 1993-03-23 | — | — | JP | disclosed |