Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 18/20 | 0.59 |
| ▸ | PPARA | Q07869 | 17/20 | 0.59 |
| ▸ | PPARD | Q03181 | 6/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7730857 | 0.90 | PPARA (0.60) | PPARGPPARAPPARD | |
| SCHEMBL7736913 | 0.89 | PPARG (0.58) | PPARGPPARAPPARD | |
| SCHEMBL7736876 | 0.89 | PPARG (0.74) | PPARGPPARAPPARD | |
| SCHEMBL5098728 | 0.87 | PPARG (0.76) | PPARGPPARAPPARD | |
| SCHEMBL14193575 | 0.82 | PPARA (0.83) | PPARGPPARAPPARD | |
| SCHEMBL5102684 | 0.81 | PPARA (0.84) | PPARGPPARAPPARD | |
| SCHEMBL7740105 | 0.80 | PPARA (0.47) | PPARGPPARAPPARD | |
| SCHEMBL14431761 | 0.79 | PPARA (0.59) | PPARGPPARAPPARD | |
| SCHEMBL4389208 | 0.79 | PPARG (0.79) | PPARGPPARAPPARD | |
| SCHEMBL10364929 | 0.78 | KDM1A (0.55) | PPARGPPARAPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0177353-B1 | THIAZOLIDINEDIONE DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1990-04-11 | — | — | EP | disclosed |
| US-4725610-A | TREATMENT OF HYPERLIPEMIA AND DIABETES | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1988-02-16 | — | — | US | disclosed |
| EP-0177353-A2 | Thiazolidinedione derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1986-04-09 | — | — | EP | disclosed |