Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 3/20 | 0.46 |
| ▸ | DRD2 | P14416 | 2/20 | 0.46 |
| ▸ | DRD4 | P21917 | 2/20 | 0.46 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.45 |
| ▸ | PGR | P06401 | 1/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.45 |
| ▸ | DRD1 | P21728 | 1/20 | 0.45 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10366377 | 1.00 | DRD3 (0.46) | DRD3DRD2DRD4ABCB1PGR | |
| SCHEMBL7317593 | 0.94 | ABCB1 (0.51) | DRD3DRD2ABCB1PGRCHRM2 | |
| SCHEMBL10368230 | 0.87 | ABCB1 (0.48) | DRD3ABCB1PGRCHRM2HTR1A | |
| SCHEMBL10368228 | 0.87 | ABCB1 (0.48) | DRD3ABCB1PGRCHRM2HTR1A | |
| SCHEMBL10369051 | 0.86 | DRD3 (0.45) | DRD3DRD2DRD4ABCB1PGR | |
| SCHEMBL10369052 | 0.86 | DRD3 (0.45) | DRD3DRD2DRD4ABCB1PGR | |
| SCHEMBL10369238 | 0.83 | MEN1 (0.43) | DRD3ABCB1PGRCHRM2HTR1A | |
| SCHEMBL10369237 | 0.83 | MEN1 (0.43) | DRD3ABCB1PGRCHRM2HTR1A | |
| SCHEMBL7315909 | 0.82 | ABCB1 (0.57) | DRD3DRD2ABCB1PGRCHRM2 | |
| SCHEMBL7315767 | 0.80 | ABCB1 (0.51) | DRD3DRD2ABCB1PGRCHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0177965-B1 | NOVEL OXA- AND THIADIAZOLYL DERIVATIVES AND THEIR USE | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1990-03-21 | — | — | EP | claimed |