Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.40 |
| ▸ | APAF1 | O14727 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.40 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.40 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.40 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | NR1I2 | O75469 | 3/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.39 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10672527 | 1.00 | KCNH2 (0.54) | KCNH2TDP1APAF1LMNATSHR | |
| SCHEMBL9624450 | 0.89 | KCNH2 (0.55) | KCNH2TDP1APAF1LMNATSHR | |
| SCHEMBL4337797 | 0.89 | KCNH2 (0.55) | KCNH2TDP1APAF1LMNATSHR | |
| SCHEMBL10504227 | 0.89 | KCNH2 (0.55) | KCNH2TDP1APAF1LMNATSHR | |
| SCHEMBL10532770 | 0.89 | KCNH2 (0.55) | KCNH2TDP1APAF1LMNATSHR | |
| SCHEMBL9624448 | 0.89 | KCNH2 (0.55) | KCNH2TDP1APAF1LMNATSHR | |
| SCHEMBL10504223 | 0.89 | KCNH2 (0.55) | KCNH2TDP1APAF1LMNATSHR | |
| SCHEMBL4337805 | 0.89 | KCNH2 (0.55) | KCNH2TDP1APAF1LMNATSHR | |
| SCHEMBL10528896 | 0.88 | KCNH2 (0.56) | KCNH2TDP1APAF1LMNATSHR | |
| SCHEMBL10528910 | 0.88 | KCNH2 (0.56) | KCNH2TDP1APAF1LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0111281-B1 | NEW CEPHEM COMPOUNDS AND PROCESSES FOR PREPARATION THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1990-06-06 | — | — | EP | disclosed |
| US-4719206-A | ANTIBIOTICS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-01-12 | — | — | US | disclosed |
| US-4584290-A | MICROBIOCIDES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1986-04-22 | — | — | US | disclosed |
| EP-0111281-A2 | New cephem compounds and processes for preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1984-06-20 | — | — | EP | disclosed |