Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.55 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.44 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.44 |
| ▸ | NR1I2 | O75469 | 4/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.42 |
| ▸ | PDE4A | P27815 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | ALB | P02768 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.41 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.41 |
| ▸ | SLC22A11 | Q9NSA0 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4337797 | 1.00 | KCNH2 (0.55) | KCNH2PTGS1ABCB11PDE4DNR1I2 | |
| SCHEMBL10504223 | 0.93 | KCNH2 (0.55) | KCNH2PTGS1ABCB11PDE4DNR1I2 | |
| SCHEMBL9624450 | 0.93 | KCNH2 (0.55) | KCNH2PTGS1ABCB11PDE4DNR1I2 | |
| SCHEMBL10532770 | 0.93 | KCNH2 (0.55) | KCNH2PTGS1ABCB11PDE4DNR1I2 | |
| SCHEMBL9624448 | 0.93 | KCNH2 (0.55) | KCNH2PTGS1ABCB11PDE4DNR1I2 | |
| SCHEMBL10504227 | 0.93 | KCNH2 (0.55) | KCNH2PTGS1ABCB11PDE4DNR1I2 | |
| Hydrochloric Acid SCHEMBL10796057 | 0.91 | KCNH2 (0.52) | KCNH2PTGS1ABCB11PDE4DNR1I2 | |
| Hydrochloric Acid SCHEMBL10796066 | 0.91 | KCNH2 (0.52) | KCNH2PTGS1ABCB11PDE4DNR1I2 | |
| Hydrochloric Acid SCHEMBL10796052 | 0.91 | KCNH2 (0.52) | KCNH2PTGS1ABCB11PDE4DNR1I2 | |
| SCHEMBL10367139 | 0.89 | KCNH2 (0.54) | KCNH2PTGS1ABCB11PDE4DNR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9476087-B2 | Methods and compounds for detecting beta-lactamase activity | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2016-10-25 | — | — | US | disclosed |
| US-20140322739-A1 | METHODS AND COMPOUNDS FOR DETECTING BETA-LACTAMASE ACTIVITY | UNIV NANYANG TECH (SG) | 2014-10-30 | — | — | US | disclosed |
| US-8802387-B2 | Methods and compounds for detecting beta-lactamase activity | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2014-08-12 | — | — | US | disclosed |
| US-20090275065-A1 | METHODS AND COMPOUNDS FOR DETECTING BETA-LACTAMASE ACTIVITY | NANYANG TECHNOLOGICAL UNIVERSITY | 2009-11-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140322739-A1 | METHODS AND COMPOUNDS FOR DETECTING BETA-LACTAMASE ACTIVITY | LPO, MPO, GUSB | KCNH2 3923/4885PTGS1 4211/4885ABCB11 1813/4885 |
| US-20090275065-A1 | METHODS AND COMPOUNDS FOR DETECTING BETA-LACTAMASE ACTIVITY | LPO, MPO, GUSB | KCNH2 3937/4885PTGS1 4249/4885ABCB11 1838/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.