Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 3/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | CASP7 | P55210 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10574485 | 0.82 | TAAR1 (0.40) | HTR2CHTR2AHTR2BALDH1A1 | |
| SCHEMBL10367170 | 0.82 | MAOB (0.48) | CYP19A1CYP3A4KDM4E | |
| SCHEMBL10366996 | 0.80 | KDM4E (0.40) | KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL10365622 | 0.79 | CFTR (0.40) | HTR2CHTR2AHTR2B | |
| SCHEMBL10366584 | 0.79 | MAOB (0.41) | HTR2CCYP19A1CYP3A4KDM4EHPGD | |
| SCHEMBL10574481 | 0.77 | MAOB (0.45) | CYP19A1CYP3A4 | |
| SCHEMBL9379992 | 0.77 | CYP19A1 (0.36) | CYP19A1KDM4EALDH1A1HSD17B10 | |
| SCHEMBL10365195 | 0.75 | KDM4E (0.46) | CYP19A1CYP3A4KDM4EALDH1A1HPGD | |
| SCHEMBL10366995 | 0.75 | MEN1 (0.44) | KDM4EALDH1A1HPGDHSD17B10GLA | |
| SCHEMBL10365621 | 0.74 | RET (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0250265-B1 | 2-PHENYLBENZOXEPIN DERIVATIVE | SUNTORY LIMITED (JP) | 1990-09-05 | — | — | EP | disclosed |
| US-4845094-A | HYPOGLYCEMIC, ANTICOAGULANT | SUNTORY LIMITED (JP) | 1989-07-04 | — | — | US | disclosed |
| EP-0250265-A1 | 2-Phenylbenzoxepin derivative | SUNTORY LIMITED (JP) | 1987-12-23 | — | — | EP | disclosed |