Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | KDM1A | O60341 | 2/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10574481 | 0.85 | MAOB (0.45) | MAOBMAPTCYP19A1CYP3A4 | |
| SCHEMBL10365192 | 0.85 | ABCG2 (0.51) | MAOBMAPTMEN1KMT2ATDP1 | |
| SCHEMBL10367118 | 0.85 | CYP19A1 (0.58) | MAOBMAPTMEN1KMT2ATDP1 | |
| SCHEMBL10366584 | 0.85 | MAOB (0.41) | MAOBMAPTKDM1AMAOAKDM4E | |
| SCHEMBL10366995 | 0.83 | MEN1 (0.44) | MAPTNPC1RAB9AMEN1KMT2A | |
| SCHEMBL9379992 | 0.83 | CYP19A1 (0.36) | MAOBMEN1KMT2AKDM4ECYP19A1 | |
| SCHEMBL10365621 | 0.83 | RET (0.42) | MAOBAR | |
| SCHEMBL10367171 | 0.82 | HTR2C (0.43) | KDM4ECYP19A1CYP3A4 | |
| SCHEMBL10574485 | 0.77 | TAAR1 (0.40) | MAOBKDM1AMAOAAR | |
| SCHEMBL10365195 | 0.76 | KDM4E (0.46) | MEN1KMT2ATDP1KDM4ECYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0250265-B1 | 2-PHENYLBENZOXEPIN DERIVATIVE | SUNTORY LIMITED (JP) | 1990-09-05 | — | — | EP | disclosed |
| US-4845094-A | HYPOGLYCEMIC, ANTICOAGULANT | SUNTORY LIMITED (JP) | 1989-07-04 | — | — | US | disclosed |
| EP-0250265-A1 | 2-Phenylbenzoxepin derivative | SUNTORY LIMITED (JP) | 1987-12-23 | — | — | EP | disclosed |