Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.37 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.37 |
| ▸ | DHFR | P00374 | 1/20 | 0.37 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | ANPEP | P15144 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3888886 | 0.83 | CALM1 (0.50) | IDO1KCNH2FFAR1FFAR4CALM1 | |
| SCHEMBL10366734 | 0.82 | IDO1 (0.44) | IDO1KCNH2FFAR1FFAR4ALDH1A1 | |
| SCHEMBL5700795 | 0.79 | FFAR1 (0.49) | KCNH2FFAR1FFAR4ALDH1A1LOXL2 | |
| SCHEMBL7786785 | 0.77 | KCNH2 (0.40) | IDO1KCNH2FFAR1FFAR4DHFR | |
| SCHEMBL14085350 | 0.77 | HTR2A (0.46) | KCNH2FFAR1FFAR4DHFRLOXL2 | |
| SCHEMBL6722156 | 0.77 | TDP1 (0.46) | IDO1KCNH2FFAR1FFAR4CALM1 | |
| SCHEMBL3218912 | 0.77 | KCNH2 (0.51) | KCNH2FFAR1FFAR4DHFRCALM1 | |
| SCHEMBL6722153 | 0.77 | FFAR1 (0.41) | IDO1KCNH2FFAR1FFAR4CALM1 | |
| SCHEMBL28175144 | 0.76 | GRM5 (0.51) | IDO1KCNH2FFAR1FFAR4GRM5 | |
| SCHEMBL6722509 | 0.74 | KDM4E (0.44) | KCNH2FFAR1FFAR4CALM1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0164075-B1 | 7-OXABICYCLOHEPTANE SUBSTITUTED THIO PROSTAGLANDIN ANALOGS | E.R. Squibb & Sons, Inc. (US) | 1990-09-12 | — | — | EP | disclosed |
| US-4560698-A | ANTIINFLAMMATORY, ANALGESIC, ANTICOAGULANT, BRONCHODILATOR, VASODILATION, ENZYME INHIBITORS | E. R. SQUIBB & SONS, INC. (US) | 1985-12-24 | — | — | US | disclosed |
| EP-0164075-A2 | 7-Oxabicycloheptane substituted thio prostaglandin analogs | E.R. Squibb & Sons, Inc. (US) | 1985-12-11 | — | — | EP | disclosed |