Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | GAA | P10253 | 1/20 | 0.61 |
| ▸ | TSHR | P16473 | 2/20 | 0.58 |
| ▸ | KDM1A | O60341 | 1/20 | 0.56 |
| ▸ | MAOB | P27338 | 1/20 | 0.56 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.55 |
| ▸ | CPB1 | P15086 | 1/20 | 0.53 |
| ▸ | CTSL | P07711 | 1/20 | 0.50 |
| ▸ | CTSB | P07858 | 1/20 | 0.50 |
| ▸ | CTSK | P43235 | 1/20 | 0.50 |
| ▸ | TLR4 | O00206 | 1/20 | 0.49 |
| ▸ | DPP4 | P27487 | 4/20 | 0.48 |
| ▸ | DPP7 | Q9UHL4 | 4/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25568205 | 0.87 | ALDH1A1 (0.67) | ALDH1A1GAATSHRKDM1AMAOB | |
| SCHEMBL20064074 | 0.86 | ALDH1A1 (0.65) | ALDH1A1GAATSHRKDM1AMAOB | |
| SCHEMBL14646988 | 0.86 | ALDH1A1 (0.65) | ALDH1A1GAATSHRKDM1AMAOB | |
| SCHEMBL16494881 | 0.86 | ALDH1A1 (0.65) | ALDH1A1GAATSHRKDM1AMAOB | |
| SCHEMBL25568201 | 0.85 | TSHR (0.64) | ALDH1A1GAATSHRKDM1AMAOB | |
| SCHEMBL25568203 | 0.85 | TSHR (0.64) | ALDH1A1GAATSHRKDM1AMAOB | |
| SCHEMBL562870 | 0.83 | ALDH1A1 (0.68) | ALDH1A1GAATSHRKDM1AMAOB | |
| SCHEMBL2055529 | 0.82 | ALDH1A1 (0.61) | ALDH1A1GAATSHRKDM1AMAOB | |
| SCHEMBL11568878 | 0.82 | ALDH1A1 (0.61) | ALDH1A1GAATSHRKDM1AMAOB | |
| SCHEMBL3948456 | 0.82 | ALDH1A1 (0.85) | ALDH1A1GAATSHRKDM1AMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0183271-B1 | LYSIN DERIVATIVE AND PROTEINASE INHIBITOR | Okamoto, Shosuke (JP) | 1990-05-16 | — | — | EP | disclosed |