Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR1 | Q9Y271 | 12/20 | 0.63 |
| ▸ | CYSLTR2 | Q9NS75 | 11/20 | 0.63 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.56 |
| ▸ | PPARG | P37231 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10370463 | 0.89 | CYSLTR1 (0.55) | CYSLTR1CYSLTR2EPHX2PPARG | |
| SCHEMBL10368401 | 0.87 | CYSLTR2 (0.69) | CYSLTR1CYSLTR2 | |
| SCHEMBL9479001 | 0.86 | CYSLTR1 (0.60) | CYSLTR1CYSLTR2EPHX2PPARG | |
| SCHEMBL9479233 | 0.86 | CYSLTR2 (0.60) | CYSLTR1CYSLTR2 | |
| SCHEMBL4452510 | 0.85 | CYSLTR1 (0.57) | CYSLTR1CYSLTR2EPHX2PPARG | |
| SCHEMBL4468802 | 0.83 | CYSLTR1 (0.82) | CYSLTR1CYSLTR2EPHX2PPARG | |
| SCHEMBL4461772 | 0.82 | CYSLTR1 (0.61) | CYSLTR1CYSLTR2EPHX2PPARG | |
| SCHEMBL9481066 | 0.82 | CYSLTR1 (0.80) | CYSLTR1CYSLTR2EPHX2PPARG | |
| Benzene SCHEMBL9478946 | 0.81 | CYSLTR2 (0.53) | CYSLTR1CYSLTR2 | |
| SCHEMBL9478845 | 0.80 | CYSLTR1 (0.54) | CYSLTR1CYSLTR2EPHX2PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0179619-B1 | HETEROCYCLIC AMIDES | ICI AMERICAS INC. (US) | 1990-09-05 | — | — | EP | claimed |
| EP-0179619-A1 | Heterocyclic amides | ICI AMERICAS INC. (US) | 1986-04-30 | — | — | EP | claimed |