Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 9/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | TYK2 | P29597 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | HPGDS | O60760 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CTSB | P07858 | 1/20 | 0.41 |
| ▸ | CTSS | P25774 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 1/20 | 0.41 |
| ▸ | CTSC | P53634 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10366777 | 0.88 | CNR1 (0.55) | NPC1RAB9AALDH1A1CNR1CNR2 | |
| SCHEMBL10368254 | 0.88 | CNR1 (0.52) | MAPK14NPC1RAB9ACNR1CNR2 | |
| SCHEMBL10366707 | 0.88 | POLB (0.52) | MAPK14NPC1RAB9ACNR1CNR2 | |
| SCHEMBL10365918 | 0.83 | CNR1 (0.50) | NPC1RAB9ACNR1CNR2PDE4B | |
| SCHEMBL10367092 | 0.83 | MAPK14 (0.52) | MAPK14NPC1RAB9AALDH1A1KDM4E | |
| SCHEMBL10366036 | 0.81 | CNR1 (0.53) | NPC1RAB9ACNR1CNR2MEN1 | |
| SCHEMBL10366679 | 0.80 | MAPK14 (0.46) | MAPK14ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL10893230 | 0.79 | MAPK14 (0.53) | MAPK14SMN1; SMN2KDM4EMEN1KMT2A | |
| SCHEMBL10369901 | 0.79 | PDE4B (0.48) | CTSKPDE4BPDE4D | |
| SCHEMBL10366047 | 0.77 | CNR1 (0.41) | NPC1RAB9ATYK2TP53HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0151867-B1 | CYANOPYRAZOLE HERBICIDES | ELI LILLY AND COMPANY (US) | 1990-01-10 | — | — | EP | disclosed |
| US-4589905-A | TERRESTRIAL AND AQUATIC APPLICATIONS | ELI LILLY AND COMPANY (US) | 1986-05-20 | — | — | US | disclosed |