Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATP4A | P20648 | 9/20 | 0.53 |
| ▸ | ATP4B | P51164 | 9/20 | 0.53 |
| ▸ | ATP1A1 | P05023 | 3/20 | 0.43 |
| ▸ | ATP1B1 | P05026 | 3/20 | 0.43 |
| ▸ | ATP1A3 | P13637 | 3/20 | 0.43 |
| ▸ | ATP1B2 | P14415 | 3/20 | 0.43 |
| ▸ | ATP1A2 | P50993 | 3/20 | 0.43 |
| ▸ | ATP1B3 | P54709 | 3/20 | 0.43 |
| ▸ | FXYD2 | P54710 | 3/20 | 0.43 |
| ▸ | ATP1A4 | Q13733 | 3/20 | 0.43 |
| ▸ | BRS3 | P32247 | 2/20 | 0.39 |
| ▸ | WDR5 | P61964 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | DDAH1 | O94760 | 2/20 | 0.38 |
| ▸ | ENGASE | Q8NFI3 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10938274 | 0.94 | ATP4A (0.47) | ATP4AATP4BATP1A1ATP1B1ATP1A3 | |
| SCHEMBL6877417 | 0.93 | ATP4A (0.49) | ATP4AATP4BATP1A1ATP1B1ATP1A3 | |
| SCHEMBL6879443 | 0.92 | ATP4A (0.64) | ATP4AATP4BATP1A1ATP1B1ATP1A3 | |
| SCHEMBL10938269 | 0.90 | ATP4A (0.44) | ATP4AATP4BATP1A1ATP1B1ATP1A3 | |
| SCHEMBL10376269 | 0.89 | ATP4A (0.43) | ATP4AATP4BATP1A1ATP1B1ATP1A3 | |
| SCHEMBL10369611 | 0.89 | ATP4A (0.42) | ATP4AATP4BATP1A1ATP1B1ATP1A3 | |
| SCHEMBL9688948 | 0.88 | ATP4A (0.44) | ATP4AATP4BATP1A1ATP1B1ATP1A3 | |
| SCHEMBL6878716 | 0.88 | ATP4A (0.43) | ATP4AATP4BATP1A1ATP1B1ATP1A3 | |
| SCHEMBL6878700 | 0.87 | ATP4A (0.43) | ATP4AATP4BATP1A1ATP1B1ATP1A3 | |
| SCHEMBL9793531 | 0.87 | BRS3 (0.41) | ATP4AATP4BATP1A1ATP1B1ATP1A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0127763-B1 | TRICYCLIC ETHERS, PROCESS FOR THEIR PREPARATION, THEIR USE AND MEDICAMENTS CONTAINING THEM | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 1990-01-24 | — | — | EP | disclosed |
| US-4560693-A | ANTISECRETORY, ANTIULCER AGENTS | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1985-12-24 | — | — | US | disclosed |
| EP-0127763-A1 | Tricyclic ethers, process for their preparation, their use and medicaments containing them | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 1984-12-12 | — | — | EP | disclosed |