Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.52 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.52 |
| ▸ | TRPM8 | Q7Z2W7 | 8/20 | 0.48 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.43 |
| ▸ | CETP | P11597 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1315919 | 0.92 | TRPM8 (0.42) | LPAR3LPAR2TRPM8 | |
| SCHEMBL1313868 | 0.84 | CHRM1 (0.36) | — | |
| SCHEMBL339477 | 0.81 | LPAR3 (0.48) | LPAR3LPAR2TRPM8ACE2CETP | |
| SCHEMBL11174705 | 0.79 | TRPM8 (0.61) | LPAR3LPAR2TRPM8 | |
| SCHEMBL5955984 | 0.79 | TRPM8 (0.61) | LPAR3LPAR2TRPM8 | |
| SCHEMBL339910 | 0.79 | LPAR3 (0.45) | LPAR3LPAR2TRPM8 | |
| SCHEMBL338061 | 0.78 | LPAR3 (0.48) | LPAR3LPAR2TRPM8 | |
| SCHEMBL17626440 | 0.77 | TRPM8 (0.60) | LPAR3LPAR2TRPM8 | |
| SCHEMBL30481398 | 0.77 | LPAR3 (0.47) | LPAR3LPAR2TRPM8 | |
| SCHEMBL30481437 | 0.77 | LPAR3 (0.47) | LPAR3LPAR2TRPM8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1832596-B1 | Compounds of mono-carboxyl functionalised dialkylphosphine acids and other components | CLARIANT FINANCE BVI LTD (VG) | 2011-01-26 | — | — | EP | disclosed |
| EP-1832596-A1 | Compounds of mono-carboxyl functionalised dialkylphosphine acids and other components | CLARIANT INTERNATIONAL LTD. (CH) | 2007-09-12 | — | — | EP | disclosed |