Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 10/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | IDE | P14735 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10370127 | 0.90 | MCHR1 (0.54) | MCHR1KDM4EALDH1A1LMNAMAPT | |
| SCHEMBL10370849 | 0.89 | MCHR1 (0.53) | MCHR1KDM4EALDH1A1LMNAMAPT | |
| SCHEMBL10368569 | 0.88 | HRH3 (0.51) | MCHR1KDM4EALDH1A1LMNAMAPT | |
| SCHEMBL10368910 | 0.87 | CYP2D6 (0.45) | MCHR1KDM4ECYP2D6 | |
| SCHEMBL10369412 | 0.86 | HRH3 (0.53) | MCHR1KDM4EALDH1A1LMNAMAPT | |
| SCHEMBL10371164 | 0.86 | HRH3 (0.53) | MCHR1KDM4EALDH1A1LMNAMAPT | |
| SCHEMBL10371673 | 0.84 | KDM4E (0.64) | MCHR1KDM4EALDH1A1LMNAMAPT | |
| SCHEMBL10368059 | 0.83 | MCHR1 (0.46) | MCHR1KDM4EALDH1A1LMNAMAPT | |
| SCHEMBL10370852 | 0.82 | HRH3 (0.54) | MCHR1KDM4EALDH1A1LMNAMAPT | |
| SCHEMBL10371564 | 0.82 | SLC2A1 (0.47) | MCHR1LMNAMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0090972-B1 | INDAZOLE DERIVATIVES | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1990-05-30 | — | — | EP | disclosed |