Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.64 |
| ▸ | MAPT | P10636 | 2/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.64 |
| ▸ | IDE | P14735 | 1/20 | 0.64 |
| ▸ | HPGD | P15428 | 1/20 | 0.64 |
| ▸ | HTT | P42858 | 1/20 | 0.64 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | CDC7 | O00311 | 1/20 | 0.53 |
| ▸ | FLT3 | P36888 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.47 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.47 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.47 |
| ▸ | ITGAL | P20701 | 1/20 | 0.47 |
| ▸ | EIF2AK2 | P19525 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10368569 | 0.90 | HRH3 (0.51) | KDM4EMAPTALDH1A1LMNAIDE | |
| SCHEMBL10371164 | 0.88 | HRH3 (0.53) | KDM4EMAPTALDH1A1LMNAIDE | |
| SCHEMBL10369412 | 0.88 | HRH3 (0.53) | KDM4EMAPTALDH1A1LMNAIDE | |
| SCHEMBL10371678 | 0.86 | CDC7 (0.51) | KDM4EMAPTALDH1A1LMNAIDE | |
| SCHEMBL10370127 | 0.85 | MCHR1 (0.54) | KDM4EMAPTALDH1A1LMNAIDE | |
| SCHEMBL10370145 | 0.84 | MCHR1 (0.53) | KDM4EMAPTALDH1A1LMNAIDE | |
| SCHEMBL10370849 | 0.84 | MCHR1 (0.53) | KDM4EMAPTALDH1A1LMNAIDE | |
| SCHEMBL10370852 | 0.84 | HRH3 (0.54) | KDM4EMAPTALDH1A1LMNAIDE | |
| SCHEMBL10367734 | 0.83 | KDM4E (0.57) | KDM4EMAPTALDH1A1LMNAHTT | |
| Hydrochloric Acid SCHEMBL10369259 | 0.82 | KDM4E (0.56) | KDM4EMAPTALDH1A1LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0090972-B1 | INDAZOLE DERIVATIVES | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1990-05-30 | — | — | EP | disclosed |
| US-4533731-A | ANTIINFLAMMATORY AGENTS | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1985-08-06 | — | — | US | disclosed |
| EP-0090972-A2 | Indazole derivatives | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1983-10-12 | — | — | EP | disclosed |