SCHEMBL10370247

SCHEMBL10370247

COc1cccc(N(C)C(=O)Cl)n1

nearest known ligand 0.45

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
NR1I2 O75469 1/20 0.45
LMNA P02545 1/20 0.45
MAOA P21397 1/20 0.45
HTR2A P28223 1/20 0.45
OPRK1 P41145 1/20 0.45
TAAR1 Q96RJ0 1/20 0.37
POLB P06746 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
OXTR P30559 2/20 0.36
CNR1 P21554 1/20 0.36
NNMT P40261 1/20 0.36
BTK Q06187 1/20 0.36
ALOX5 P09917 2/20 0.35
MAPT P10636 1/20 0.35
MAPK1 P28482 1/20 0.35
GPBAR1 Q8TDU6 1/20 0.35
FGFR4 P22455 1/20 0.34
MTNR1A P48039 2/20 0.34
MTNR1B P49286 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9667393 0.85 NR1I2 (0.46) NR1I2LMNAMAOAHTR2AOPRK1
SCHEMBL14067085 0.85 NR1I2 (0.46) NR1I2LMNAMAOAHTR2AOPRK1
SCHEMBL8464945 0.83 NR1I2 (0.45) NR1I2LMNAMAOAHTR2AOPRK1
SCHEMBL2474604 0.83 NR1I2 (0.54) NR1I2LMNAMAOAHTR2AOPRK1
SCHEMBL18073997 0.81 NR1I2 (0.43) NR1I2LMNAMAOAHTR2AOPRK1
SCHEMBL4072458 0.78 NR1I2 (0.42) NR1I2LMNAMAOAHTR2AOPRK1
SCHEMBL29710014 0.78 HTR2A (0.40) NR1I2LMNAMAOAHTR2AOPRK1
SCHEMBL21232691 0.78 HTR2A (0.40) NR1I2LMNAMAOAHTR2AOPRK1
SCHEMBL8464946 0.78 NR1I2 (0.52) NR1I2LMNAMAOAHTR2AOPRK1
SCHEMBL13150446 0.77 NR1I2 (0.51) NR1I2LMNAMAOAHTR2AOPRK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0194562-B1 FUNGICIDAL COMPOSITION TOSOH CORPORATION (JP) 1990-10-03 EP disclosed
US-4826859-A Fungicidal methods containing N-pyridylcarbamates TOSOH CORPORATION (JP) 1989-05-02 US disclosed
EP-0194562-A1 Fungicidal composition TOSOH CORPORATION (JP) 1986-09-17 EP disclosed
US-4554012-A HERBICIDES TOYO SODA MANUFACTURING CO., LTD. (JP) 1985-11-19 US disclosed