SCHEMBL8464946

SCHEMBL8464946

COc1cccc(N(C)C(O)=S)n1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NR1I2 O75469 1/20 0.52
LMNA P02545 1/20 0.52
MAOA P21397 1/20 0.52
HTR2A P28223 1/20 0.52
OPRK1 P41145 1/20 0.52
TAAR1 Q96RJ0 1/20 0.38
PHGDH O43175 2/20 0.34
FAAH O00519 1/20 0.34
MGLL Q99685 1/20 0.34
POLB P06746 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
OXTR P30559 1/20 0.34
ALOX5 P09917 2/20 0.33
BTK Q06187 1/20 0.33
KDR P35968 2/20 0.33
FGFR1 P11362 1/20 0.33
EPHB4 P54760 1/20 0.33
MTNR1A P48039 2/20 0.33
MTNR1B P49286 2/20 0.33
MAPT P10636 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13150446 0.85 NR1I2 (0.51) NR1I2LMNAMAOAHTR2AOPRK1
SCHEMBL2474604 0.85 NR1I2 (0.54) NR1I2LMNAMAOAHTR2AOPRK1
SCHEMBL10716810 0.83 NR1I2 (0.50) NR1I2LMNAMAOAHTR2AOPRK1
SCHEMBL9667393 0.83 NR1I2 (0.46) NR1I2LMNAMAOAHTR2AOPRK1
SCHEMBL14067085 0.79 NR1I2 (0.46) NR1I2LMNAMAOAHTR2AOPRK1
SCHEMBL10570347 0.79 NR1I2 (0.52) NR1I2LMNAMAOAHTR2AOPRK1
SCHEMBL10370835 0.78 NCF1 (0.38) NR1I2LMNAMAOAHTR2AOPRK1
SCHEMBL10370247 0.78 NR1I2 (0.45) NR1I2LMNAMAOAHTR2AOPRK1
SCHEMBL8464945 0.78 NR1I2 (0.45) NR1I2LMNAMAOAHTR2AOPRK1
SCHEMBL9665437 0.77 MEN1 (0.43) LMNAPHGDHFAAHMGLLKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0714602-B1 Sulphonylaminophenyluracil herbicides for paddy field BAYER AGROCHEM KK (JP) 1999-05-12 EP claimed
EP-0341754-B1 USE OF CARBAMATE OR THIOCARBAMATE DERIVATIVES FOR TREATMENT OF FUNGAL INFECTIONS Tosoh Corporation (JP) 1992-12-09 EP claimed
EP-0194562-B1 FUNGICIDAL COMPOSITION TOSOH CORPORATION (JP) 1990-10-03 EP claimed
EP-0144570-B1 ANTIFUNGAL COMPOSITIONS CONTAINING CARBAMATES TOSOH CORPORATION (JP) 1990-09-19 EP claimed
US-4621090-A Antifungal compositions TOYO SODA MANUFACTURING CO., LTD. (JP) 1986-11-04 US claimed
JP-6239706-A None JP disclosed
JP-1143805-A None JP disclosed
US-5688745-A Arylsulfonylureas and their use as herbicides and growth regulators HOECHST AKTIENGESELLSCHAFT (DE) 1997-11-18 US disclosed
JP-H06239706-A HERBICIDAL COMPOSITION FOR RICE PADDY FIELD TOSOH CORP 1994-08-30 JP disclosed
JP-H01143805-A HERBICIDAL COMPOSITION MITSUI TOATSU CHEM INC 1989-06-06 JP disclosed
US-4826859-A Fungicidal methods containing N-pyridylcarbamates TOSOH CORPORATION (JP) 1989-05-02 US disclosed