Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 3/20 | 0.61 |
| ▸ | DPP9 | Q86TI2 | 3/20 | 0.61 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.61 |
| ▸ | GABRP | O00591 | 2/20 | 0.47 |
| ▸ | GABRD | O14764 | 2/20 | 0.47 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.47 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.47 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.47 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.47 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.47 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.47 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.47 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.47 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.47 |
| ▸ | GABRE | P78334 | 2/20 | 0.47 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.47 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.47 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.47 |
| ▸ | GABRQ | Q9UN88 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10370366 | 0.86 | DPP8 (0.61) | DPP4DPP9DPP8LMNABLM | |
| SCHEMBL10162444 | 0.84 | DPP4 (0.63) | DPP4DPP9DPP8GABRPGABRD | |
| SCHEMBL10280921 | 0.82 | DPP4 (0.69) | DPP4DPP9DPP8GABRPGABRD | |
| SCHEMBL8166514 | 0.79 | DPP4 (0.56) | DPP4DPP9DPP8GABRPGABRD | |
| SCHEMBL751142 | 0.79 | DPP4 (0.65) | DPP4DPP9DPP8GABRPGABRD | |
| SCHEMBL29415456 | 0.79 | DPP4 (0.65) | DPP4DPP9DPP8GABRPGABRD | |
| SCHEMBL751143 | 0.79 | DPP4 (0.65) | DPP4DPP9DPP8GABRPGABRD | |
| SCHEMBL27996817 | 0.79 | DPP4 (0.65) | DPP4DPP9DPP8GABRPGABRD | |
| SCHEMBL10742433 | 0.77 | NOD1 (0.54) | CYP1A2GRM8GRM6GRIN2DGRIN3B | |
| SCHEMBL12118145 | 0.77 | DPP4 (0.54) | DPP4DPP9DPP8GABRPGABRD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0163550-B1 | MITOMYCIN DERIVATIVES, PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | KYOWA HAKKO KOGYO KABUSHIKI KAISHA (JP) | 1990-11-22 | — | — | EP | claimed |
| EP-0163550-A2 | Mitomycin derivatives, preparation thereof and pharmaceutical compositions containing them | KYOWA HAKKO KOGYO KABUSHIKI KAISHA (JP) | 1985-12-04 | — | — | EP | claimed |
| EP-0163550-B1 | MITOMYCIN DERIVATIVES, PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | KYOWA HAKKO KOGYO KABUSHIKI KAISHA (JP) | 1990-11-22 | — | — | EP | disclosed |
| US-4691024-A | BACTERICIDES, ANTITUMOR | KYOWA HAKKO KOGYO KABUSHIKI KAISHA (JP) | 1987-09-01 | — | — | US | disclosed |