Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | TOP2A | P11388 | 1/20 | 0.31 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25081406 | 0.88 | PIK3CD (0.42) | PIK3CDALDH1A1GAATHRBL3MBTL1 | |
| SCHEMBL25081392 | 0.81 | CHRNA7 (0.41) | PIK3CDALDH1A1GAATHRBL3MBTL1 | |
| SCHEMBL8865900 | 0.80 | PIK3CD (0.33) | PIK3CD | |
| SCHEMBL9265803 | 0.77 | PIK3CD (0.32) | PIK3CD | |
| SCHEMBL27339718 | 0.75 | — | — | |
| SCHEMBL13937974 | 0.74 | — | — | |
| SCHEMBL12706200 | 0.72 | TSHR (0.36) | ALDH1A1GAATHRBL3MBTL1TOP2A | |
| SCHEMBL178511 | 0.72 | — | — | |
| SCHEMBL6916525 | 0.71 | — | — | |
| SCHEMBL18030253 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11731987-B2 | Prolyl hydroxylase domain-containing protein (PHD) inhibitors and uses thereof | INSILICO MEDICINE IP LIMITED (HK) | 2023-08-22 | — | — | US | disclosed |
| US-11731987-B2 | Prolyl hydroxylase domain-containing protein (PHD) inhibitors and uses thereof | INSILICO MEDICINE IP LIMITED (HK) | 2023-08-22 | — | — | US | disclosed |
| US-20230192688-A1 | PROLYL HYDROXYLASE DOMAIN-CONTAINING PROTEIN (PHD) INHIBITORS AND USES THEREOF | INSILICO MEDICINE IP LIMITED (HK) | 2023-06-22 | — | — | US | disclosed |
| US-20230192688-A1 | PROLYL HYDROXYLASE DOMAIN-CONTAINING PROTEIN (PHD) INHIBITORS AND USES THEREOF | INSILICO MEDICINE IP LIMITED (HK) | 2023-06-22 | — | — | US | disclosed |
| US-10774064-B2 | Potassium channel modulators | CADENT THERAPEUTICS, INC. (US) | 2020-09-15 | — | — | US | disclosed |
| US-20190218200-A1 | POTASSIUM CHANNEL MODULATORS | NOVARTIS AG (CH) | 2019-07-18 | — | — | US | disclosed |
| WO-2017186148-A1 | NOVEL HETEROCYCLIC COMPOUNDS AS TYROSINE KINASE BCR-ABL INHIBITORS | ASTAR BIOTECH LLC (US) | 2017-11-02 | — | — | WO | disclosed |
| US-8349873-B2 | Factor XA inhibitors | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2013-01-08 | — | — | US | disclosed |
| US-20120088795-A1 | FACTOR XA INHIBITORS | MILLENNIUM PHARMACEUTICALS, INC. | 2012-04-12 | — | — | US | disclosed |
| US-20120088795-A1 | FACTOR XA INHIBITORS | MILLENNIUM PHARMACEUTICALS, INC. | 2012-04-12 | — | — | US | disclosed |
| WO-1997006225-A1 | MOTOR FUEL DETERGENT ADDITIVES | TEXACO DEVELOPMENT CORPORATION (US) | 1997-02-20 | — | — | WO | disclosed |
| US-5567211-A | ANTIDEPOSIT AGENT COMPRISING AN AMIDO ALKANOLAMINE REACTION PRODUCT OF 4-ALKYL-2-MORPHOLINONE AND AN ALKYLPHENOXYPOLYOXYALKYLENE AMINE AND A POLYISOBUTYLENE AMINE | TEXACO INC. (US) | 1996-10-22 | — | — | US | disclosed |
| US-5558684-A | REACTION PRODUCT OF 4-ALKYL-2-MORPHOLINONE AND ALKYLPHENOXYPOLYOXYALKYLENE AMINE TO PREVENT HAZE | TEXACO INC. (US) | 1996-09-24 | — | — | US | disclosed |
| US-5332407-A | Reaction product of N-alkyl-2-morpholinone and ethylene oxide-alkylphenol adduct or polymer | TEXACO INC. (US) | 1994-07-26 | — | — | US | disclosed |
| EP-0596602-A1 | Diesel fuel additive providing clean up detergency of fuel injectors | TEXACO DEVELOPMENT CORPORATION (US) | 1994-05-11 | — | — | EP | disclosed |
| US-5286264-A | Antideposit agents for intake valves and combustion chambers of internal combustion engines comprising a 4-alkylmorpholin-2-one-modified polyether; a polyalkenyl succinimide and a polyalphaolefin | TEXACO INC. (US) | 1994-02-15 | — | — | US | disclosed |
| EP-0574203-A1 | Fuel additive | TEXACO DEVELOPMENT CORPORATION (US) | 1993-12-15 | — | — | EP | disclosed |
| US-5234478-A | Amido alkanolamine obtained by reacting 4-alkyl-2-morpholine with alkylphenoxypolyoxyalkylene amine | TEXACO INC. (US) | 1993-08-10 | — | — | US | disclosed |
| US-5203879-A | An amido alkanolamine additive; amidating a polyoxyalkylene amine with a 4-alkyl-2-morpholinone | TEXACO INC. (US) | 1993-04-20 | — | — | US | disclosed |
| US-5066804-A | Preparation of alkyl morpholinones | TEXACO CHEMICAL COMPANY (US) | 1991-11-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230192688-A1 | PROLYL HYDROXYLASE DOMAIN-CONTAINING PROTEIN (PHD) INHIBITORS AND USES THEREOF | EGLN3, EGLN2, EGLN1 | PIK3CD 3006/4885ALDH1A1 1538/4885GAA 1250/4885 |
| US-10774064-B2 | Potassium channel modulators | KCNJ11, KCNJ2, KCNJ1 | PIK3CD 897/4885ALDH1A1 1320/4885GAA 1172/4885 |
| US-20190218200-A1 | POTASSIUM CHANNEL MODULATORS | KCNJ11, KCNJ2, KCNJ1 | PIK3CD 897/4885ALDH1A1 1320/4885GAA 1172/4885 |
| US-11731987-B2 | Prolyl hydroxylase domain-containing protein (PHD) inhibitors and uses thereof | EGLN3, EGLN2, EGLN1 | PIK3CD 3006/4885ALDH1A1 1538/4885GAA 1250/4885 |
| US-20120088795-A1 | FACTOR XA INHIBITORS | TFPI, F12, F11 | PIK3CD 1521/4885ALDH1A1 911/4885GAA 324/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.