Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10369083 | 1.00 | POLB (0.44) | POLBMAPTCYP2C9CYP2C19TDP1 | |
| SCHEMBL10860120 | 0.87 | POLB (0.48) | POLBMAPTCYP2C9CYP2C19TDP1 | |
| SCHEMBL10367964 | 0.87 | POLB (0.48) | POLBMAPTCYP2C9CYP2C19TDP1 | |
| SCHEMBL10860763 | 0.87 | POLB (0.48) | POLBMAPTCYP2C9CYP2C19TDP1 | |
| SCHEMBL10368703 | 0.87 | POLB (0.48) | POLBMAPTCYP2C9CYP2C19TDP1 | |
| SCHEMBL7805583 | 0.85 | TDP1 (0.40) | MAPTCYP2C9TDP1ATMACHE | |
| SCHEMBL10859825 | 0.84 | POLB (0.46) | POLBMAPTCYP2C9CYP2C19TDP1 | |
| SCHEMBL10370808 | 0.84 | POLB (0.46) | POLBMAPTCYP2C9CYP2C19TDP1 | |
| SCHEMBL10390516 | 0.84 | POLB (0.46) | POLBMAPTCYP2C9CYP2C19TDP1 | |
| SCHEMBL10369060 | 0.84 | POLB (0.46) | POLBMAPTCYP2C9CYP2C19TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0182213-B1 | CARBAPENEM COMPOUNDS AND PRODUCTION THEREOF | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1990-09-26 | — | — | EP | disclosed |