Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.60 |
| ▸ | ASPH | Q12797 | 5/20 | 0.60 |
| ▸ | KDM8 | Q8N371 | 5/20 | 0.60 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | AGER | Q15109 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | CES1 | P23141 | 1/20 | 0.37 |
| ▸ | KMO | O15229 | 5/20 | 0.37 |
| ▸ | MYC | P01106 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | KDM6B | O15054 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL644769 | 0.85 | KDM4E (0.68) | KDM4EASPHKDM8MAPTALDH1A1 | |
| SCHEMBL8664867 | 0.85 | KDM4E (0.49) | KDM4EASPHKDM8MAPTALDH1A1 | |
| SCHEMBL2114463 | 0.81 | NAPRT (0.48) | KDM4EASPHKDM8MAPTALDH1A1 | |
| SCHEMBL10765922 | 0.79 | KDM4E (0.46) | KDM4EASPHKDM8MAPTALDH1A1 | |
| SCHEMBL28048186 | 0.79 | KDM4E (0.55) | KDM4EASPHKDM8MAPTALDH1A1 | |
| SCHEMBL29525861 | 0.78 | KDM4E (0.53) | KDM4EASPHKDM8MAPTALDH1A1 | |
| SCHEMBL1478308 | 0.78 | SMN1; SMN2 (0.46) | KDM4EASPHKDM8MAPTALDH1A1 | |
| SCHEMBL21826438 | 0.78 | KDM4E (0.44) | KDM4EASPHKDM8MAPTALDH1A1 | |
| SCHEMBL28478885 | 0.78 | KDM4E (0.53) | KDM4EASPHKDM8MAPTALDH1A1 | |
| SCHEMBL28337894 | 0.78 | KDM4E (0.58) | KDM4EASPHKDM8MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101830921-A | Novel method for activating 7-halogen of fluoroquinoline-3carboxylic acid and application thereof in forming side chain with secondary amine by using condensation | LIANYUNGANG JINKANG PHARMACEUTICAL TECHNOLOGY CO LTD | 2010-09-15 | — | — | CN | disclosed |
| EP-0182769-B1 | 2,6-SUBSTITUTED PYRIDINE COMPOUNDS | Monsanto Company (US) | 1990-08-01 | — | — | EP | disclosed |
| US-4921530-A | Certain 3,5-pyridine dicarboxylates, their thio analogues having herbicidal activity | MONSANTO COMPANY (US) | 1990-05-01 | — | — | US | disclosed |
| US-4835279-A | 2,6-substituted pyridine compounds | MONSANTO COMPANY (US) | 1989-05-30 | — | — | US | disclosed |
| US-4797149-A | HERBICIDES | MONSANTO COMPANY (US) | 1989-01-10 | — | — | US | disclosed |
| US-4698093-A | POST, PRE EMERGENTS | MONSANTO COMPANY (US) | 1987-10-06 | — | — | US | disclosed |
| EP-0182769-A1 | 2,6-Substituted pyridine compounds | Monsanto Company (US) | 1986-05-28 | — | — | EP | disclosed |