⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10810342 | 1.00 | EPHX1 (0.47) | — | |
| Hydrochloric Acid SCHEMBL28974203 | 0.97 | — | — | |
| SCHEMBL21807667 | 0.91 | EPHX1 (0.41) | — | |
| SCHEMBL12166522 | 0.91 | EPHX1 (0.41) | — | |
| SCHEMBL12735561 | 0.91 | EPHX1 (0.41) | — | |
| SCHEMBL14609349 | 0.91 | EPHX1 (0.41) | — | |
| SCHEMBL966301 | 0.90 | EPHX1 (0.59) | — | |
| SCHEMBL1752291 | 0.90 | — | — | |
| SCHEMBL16230019 | 0.88 | EPHX1 (0.62) | — | |
| SCHEMBL19312134 | 0.88 | EPHX1 (0.62) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 101 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2903979-B1 | NOVEL COMPOUNDS, THEIR PREPARATION AND THEIR USES | INHIBIKASE THERAPEUTICS INC (US) | 2020-08-19 | — | — | EP | claimed |
| EP-4698224-A1 | SAPONIN DERIVATIVES AS ADJUVANTS AND PHOTOAFFINITY PROBES | Asociación Centro de Investigación Cooperativa en Biociencias - CIC bioGUNE (ES) | 2026-02-25 | — | — | EP | disclosed |
| WO-2025054361-A1 | COMPLEMENT INHIBITION | APELLIS PHARMACEUTICALS, INC. (US) | 2025-03-13 | — | — | WO | disclosed |
| WO-2024218268-A1 | SAPONIN DERIVATIVES AS ADJUVANTS AND PHOTOAFFINITY PROBES | ASOCIACIÓN CENTRO DE INVESTIGACIÓN COOPERATIVA EN BIOCIENCIAS-CIC BIOGUNE (ES) | 2024-10-24 | — | — | WO | disclosed |
| EP-4440622-A1 | SAPONIN-BASED ADJUVANTS AND VACCINES | Asociación Centro de Investigación Cooperativa en Biociencias - CIC bioGUNE (ES) | 2024-10-09 | — | — | EP | disclosed |
| US-12109207-B2 | Methods of using 4(1H)-quinolone derivatives | ACADEMIA SINICA (TW) | 2024-10-08 | — | — | US | disclosed |
| CN-118638025-A | Process for preparing (S) -4, 5-diamino-5-oxopentanoic acid tert-butyl ester | 细胞基因公司 | 2024-09-13 | — | — | CN | disclosed |
| CN-114736219-B | Antitumor compounds | 法马马有限公司 | 2024-06-07 | — | — | CN | disclosed |
| CN-114751920-B | Antitumor compounds | 法马马有限公司 | 2024-06-07 | — | — | CN | disclosed |
| CN-118055926-A | ROCK2 inhibitors and uses thereof | 哈佛大学的校长及成员们 | 2024-05-17 | — | — | CN | disclosed |
| US-5541229-A | ANGIOITENSIN II ANTAGONIST AS HYPOTENSIVE AGENTS, ANTIISCHEMIC AGENTS AND CARDIOVASCULAR DISORDERS | DR. KARL THOMAE GMBH (DE) | 1996-07-30 | — | — | US | disclosed |
| US-5446052-A | Used for treatment of substance p-and neurokinin-dependent pathology such as analgesia and inflmmation | SANOFI (FR) | 1995-08-29 | — | — | US | disclosed |
| US-5411971-A | N-alkylenepiperidino compounds, their enantiomers and pharmaceutical compositions | ELF SANOFI (FR) | 1995-05-02 | — | — | US | disclosed |
| US-5300648-A | Analgesics, antiinflammatory agents | SOCIETE ANONYME: ELF SANOFI (FR) | 1994-04-05 | — | — | US | disclosed |
| US-5254595-A | Aryloxypropanolaminotetralins, a process for their preparation and pharmaceutical compositions containing them | ELF SANOFI (FR) | 1993-10-19 | — | — | US | disclosed |
| US-5236921-A | Administrering for treatment of neutrogenic inflammation of the respiratory trart | SANOFI (FR) | 1993-08-17 | — | — | US | disclosed |
| EP-0200915-B1 | AMINOPROPANOL DERIVATIVES, PROCESS FOR THEIR PREPARATION, THEIR USE AND MEDICINES CONTAINING THEM | Roche Diagnostics GmbH (DE) | 1989-09-27 | — | — | EP | disclosed |
| US-4863949-A | CARDIOVASCULAR DISORDER TREATMENT | BOEHRINGER MANNHEIM GMBH (DE) | 1989-09-05 | — | — | US | disclosed |
| EP-0280951-A1 | Amino-propanol derivatives, process for their preparation and medicines containing these compounds, as well as intermediates | Roche Diagnostics GmbH (DE) | 1988-09-07 | — | — | EP | disclosed |
| EP-0200915-A1 | Aminopropanol derivatives, process for their preparation, their use and medicines containing them | Roche Diagnostics GmbH (DE) | 1986-11-12 | — | — | EP | disclosed |