SCHEMBL10374153

SCHEMBL10374153

CCCCCCS(=O)(=O)c1nn2c(C)cc(=O)nc2s1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 4/20 0.43
CA1 P00915 4/20 0.43
CA2 P00918 4/20 0.43
CA3 P07451 4/20 0.43
CA4 P22748 4/20 0.43
CA6 P23280 4/20 0.43
CA5A P35218 4/20 0.43
CA7 P43166 4/20 0.43
CA9 Q16790 4/20 0.43
CA13 Q8N1Q1 4/20 0.43
CA14 Q9ULX7 4/20 0.43
CA5B Q9Y2D0 4/20 0.43
KDM4E B2RXH2 2/20 0.39
KMT2A Q03164 3/20 0.34
HPGD P15428 2/20 0.33
THRB P10828 2/20 0.33
POLB P06746 1/20 0.33
ALPL P05186 1/20 0.33
ALPI P09923 1/20 0.33
MEN1 O00255 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9535428 0.84 CA2 (0.40) CA12CA1CA2CA3CA4
SCHEMBL9533394 0.84 CA2 (0.40) CA12CA1CA2CA3CA4
SCHEMBL10374150 0.83 KDM4E (0.46) CA12CA1CA2CA3CA4
SCHEMBL9531449 0.83 CA2 (0.39) CA12CA1CA2CA3CA4
SCHEMBL10373550 0.82 CA12 (0.38) CA12CA1CA2CA3CA4
SCHEMBL9534621 0.77 CA12 (0.35) CA12CA1CA2CA3CA4
SCHEMBL9534628 0.77 CA12 (0.35) CA12CA1CA2CA3CA4
SCHEMBL9535424 0.77 KDM4E (0.43) CA12CA1CA2CA3CA4
SCHEMBL9533390 0.77 KDM4E (0.43) CA12CA1CA2CA3CA4
SCHEMBL9531444 0.76 KDM4E (0.42) CA12CA1CA2CA3CA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0238997-B1 AGRICULTURAL-HORTICULTURAL FUNGICIDE KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 1990-06-20 EP disclosed
US-4742063-A Agricultural-horticultural fungicide employing 5H-1,3,4-thiadiazolo[3,2-a]py KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 1988-05-03 US disclosed
EP-0238997-A1 Agricultural-horticultural fungicide KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 1987-09-30 EP disclosed