Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 6/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.65 |
| ▸ | TOP2A | P11388 | 7/20 | 0.59 |
| ▸ | TOP2B | Q02880 | 5/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.55 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.55 |
| ▸ | TOP1 | P11387 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 5/20 | 0.53 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.49 |
| ▸ | BRD4 | O60885 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.45 |
| ▸ | ATP6V1B2 | P21281 | 1/20 | 0.45 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9088225 | 0.96 | HPGD (0.64) | HPGDHSD17B10TOP2ATOP2BKDM4E | |
| SCHEMBL10372535 | 0.93 | KDM4E (0.62) | HPGDHSD17B10TOP2ATOP2BKDM4E | |
| SCHEMBL10372207 | 0.93 | HPGD (0.56) | HPGDHSD17B10TOP2ATOP2BKDM4E | |
| SCHEMBL10374981 | 0.91 | HPGD (0.75) | HPGDHSD17B10TOP2ATOP2BKDM4E | |
| SCHEMBL10374985 | 0.90 | HPGD (0.74) | HPGDHSD17B10TOP2ATOP2BKDM4E | |
| SCHEMBL9870203 | 0.89 | KDM4E (0.66) | HPGDHSD17B10TOP2ATOP2BKDM4E | |
| SCHEMBL10915435 | 0.88 | KDM4E (0.57) | HPGDHSD17B10TOP2ATOP2BKDM4E | |
| SCHEMBL10372760 | 0.88 | KDM4E (0.57) | HPGDHSD17B10TOP2ATOP2BKDM4E | |
| Hydrochloric Acid SCHEMBL9869082 | 0.87 | KDM4E (0.59) | HPGDHSD17B10TOP2ATOP2BKDM4E | |
| SCHEMBL9869882 | 0.86 | TOP2A (0.61) | HPGDHSD17B10TOP2ATOP2BKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0154780-B1 | QUINOLINE ANTIBACTERIAL COMPOUNDS | ABBOTT LABORATORIES (US) | 1990-04-11 | — | — | EP | disclosed |
| US-4774246-A | 6,8-DIFLUORO-4-OXO-3-CARBOXYLIC ACID DERIVATIVES | ABBOTT LABORATORIES (US) | 1988-09-27 | — | — | US | disclosed |
| EP-0154780-A1 | Quinoline antibacterial compounds | ABBOTT LABORATORIES (US) | 1985-09-18 | — | — | EP | disclosed |