Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP2A | P11388 | 7/20 | 0.61 |
| ▸ | TOP2B | Q02880 | 5/20 | 0.61 |
| ▸ | TOP1 | P11387 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.55 |
| ▸ | HPGD | P15428 | 6/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.55 |
| ▸ | LMNA | P02545 | 4/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.48 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.48 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.48 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | BRD4 | O60885 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9869220 | 0.91 | HPGD (0.62) | TOP2ATOP2BTOP1ALDH1A1KDM4E | |
| SCHEMBL9088225 | 0.90 | HPGD (0.64) | TOP2ATOP2BTOP1ALDH1A1KDM4E | |
| SCHEMBL10914429 | 0.89 | TOP2A (0.49) | TOP2ATOP2BTOP1ALDH1A1KDM4E | |
| SCHEMBL9869795 | 0.88 | KDM4E (0.58) | TOP2ATOP2BTOP1ALDH1A1KDM4E | |
| SCHEMBL9869932 | 0.87 | ALDH1A1 (0.62) | TOP2ATOP2BALDH1A1KDM4EHPGD | |
| SCHEMBL29690159 | 0.87 | TOP2A (0.56) | TOP2ATOP2BTOP1ALDH1A1KDM4E | |
| SCHEMBL28942268 | 0.87 | TOP2A (0.56) | TOP2ATOP2BTOP1ALDH1A1KDM4E | |
| SCHEMBL10375142 | 0.86 | HPGD (0.65) | TOP2ATOP2BTOP1ALDH1A1KDM4E | |
| SCHEMBL10769256 | 0.85 | TOP2A (0.59) | TOP2ATOP2BTOP1ALDH1A1KDM4E | |
| SCHEMBL29690006 | 0.85 | TOP2A (0.59) | TOP2ATOP2BTOP1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4981854-A | BACTERICIDES, ANIMAL GROWTH REGUALTORS | BAYER AKTIENGESELLSCHAFT (DE) | 1991-01-01 | — | — | US | claimed |
| US-4980353-A | BACTERICIDES, ANIMAL GROWTH REGULATORS | BAYER AKTIENGESELLSCHAFT (DE) | 1990-12-25 | — | — | US | claimed |
| EP-0201829-A1 | 1-Aryl-4-quinolone-3-carboxylic acids | BAYER AG (DE) | 1986-11-20 | — | — | EP | claimed |
| US-4981854-A | BACTERICIDES, ANIMAL GROWTH REGUALTORS | BAYER AKTIENGESELLSCHAFT (DE) | 1991-01-01 | — | — | US | disclosed |
| US-4980353-A | BACTERICIDES, ANIMAL GROWTH REGULATORS | BAYER AKTIENGESELLSCHAFT (DE) | 1990-12-25 | — | — | US | disclosed |
| EP-0201829-A1 | 1-Aryl-4-quinolone-3-carboxylic acids | BAYER AG (DE) | 1986-11-20 | — | — | EP | disclosed |