Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 6/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | POLB | P06746 | 3/20 | 0.55 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.55 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.55 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.55 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | HPGD | P15428 | 3/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | CLK2 | P49760 | 1/20 | 0.54 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | TOP2A | P11388 | 5/20 | 0.53 |
| ▸ | TOP2B | Q02880 | 5/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10374229 | 0.92 | ALDH1A1 (0.67) | KCNH2ALDH1A1POLBOPRM1CHRM2 | |
| SCHEMBL10373997 | 0.89 | KCNH2 (0.54) | KCNH2ALDH1A1POLBOPRM1CHRM2 | |
| SCHEMBL9665913 | 0.88 | KCNH2 (0.71) | KCNH2ALDH1A1POLBOPRM1CHRM2 | |
| Hydrochloric Acid SCHEMBL7851149 | 0.88 | KCNH2 (0.57) | KCNH2ALDH1A1POLBOPRM1CHRM2 | |
| Hydrochloric Acid SCHEMBL7851152 | 0.88 | KCNH2 (0.57) | KCNH2ALDH1A1POLBOPRM1CHRM2 | |
| Hydrochloric Acid SCHEMBL7851158 | 0.88 | KCNH2 (0.57) | KCNH2ALDH1A1POLBOPRM1CHRM2 | |
| SCHEMBL10373922 | 0.87 | ALDH1A1 (0.60) | KCNH2ALDH1A1POLBOPRM1CHRM2 | |
| SCHEMBL10373920 | 0.87 | ALDH1A1 (0.60) | KCNH2ALDH1A1POLBOPRM1CHRM2 | |
| SCHEMBL9372930 | 0.87 | ALDH1A1 (0.60) | KCNH2ALDH1A1POLBOPRM1CHRM2 | |
| SCHEMBL10376058 | 0.87 | KCNH2 (0.52) | KCNH2ALDH1A1POLBOPRM1CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4753953-A | Pyridonecarboxylic acid derivatives and antibacterial pharmaceutical compositions thereof | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1988-06-28 | — | — | US | claimed |
| EP-0208210-B1 | PYRIDONECARBOXYLIC ACID DERIVATIVES AND PROCESS FOR THEIR PREPARATION | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1990-10-24 | — | — | EP | disclosed |
| US-4753953-A | Pyridonecarboxylic acid derivatives and antibacterial pharmaceutical compositions thereof | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1988-06-28 | — | — | US | disclosed |