Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.43 |
| ▸ | CCR5 | P51681 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10375206 | 0.90 | PDE4D (0.56) | USP2POLBALDH1A1MAPTL3MBTL1 | |
| Fumaric Acid SCHEMBL10375333 | 0.86 | PDE4D (0.52) | USP2ALDH1A1MAPTL3MBTL1PDE4D | |
| Fumaric Acid SCHEMBL10375332 | 0.86 | PDE4D (0.52) | USP2ALDH1A1MAPTL3MBTL1PDE4D | |
| SCHEMBL10755741 | 0.85 | ERN1 (0.45) | USP2POLBALDH1A1MAPTL3MBTL1 | |
| SCHEMBL10377149 | 0.85 | USP2 (0.49) | USP2POLBALDH1A1MAPTL3MBTL1 | |
| SCHEMBL10377218 | 0.85 | PDE4D (0.53) | POLBALDH1A1MAPTL3MBTL1PDE4D | |
| SCHEMBL10375266 | 0.84 | PDE4D (0.56) | ALDH1A1MAPTL3MBTL1PDE4DLMNA | |
| SCHEMBL10376659 | 0.82 | KMT2A (0.51) | POLBALDH1A1MAPTKMT2ALMNA | |
| SCHEMBL10377529 | 0.82 | MAPT (0.47) | USP2POLBALDH1A1MAPTHPGD | |
| SCHEMBL10375299 | 0.81 | KMT2A (0.54) | POLBALDH1A1MAPTL3MBTL1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0169712-B1 | NEW PYRIMIDINE DERIVATIVES, PROCESSES FOR PREPARATION THEREOF AND COMPOSITION CONTAINING THE SAME | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1990-12-12 | — | — | EP | disclosed |
| US-4698340-A | TREATMENT OF CEREBROVASCULAR DISEASES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1987-10-06 | — | — | US | disclosed |
| EP-0169712-A2 | New pyrimidine derivatives, processes for preparation thereof and composition containing the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1986-01-29 | — | — | EP | disclosed |