Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 3/20 | 0.55 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.55 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.55 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.53 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.53 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.53 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.53 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10672729 | 0.87 | GABRA1 (0.61) | GABRA1GABRA6GABRB2GABRA3GABRG2 | |
| SCHEMBL10365915 | 0.86 | GABRA1 (0.53) | GABRA1GABRA6GABRA3GABRG2GABRB3 | |
| SCHEMBL10659542 | 0.84 | GABRA1 (0.60) | GABRA1GABRA6GABRB2GABRA3GABRG2 | |
| SCHEMBL6649418 | 0.84 | GABRA1 (0.60) | GABRA1GABRA6GABRB2GABRA3GABRG2 | |
| SCHEMBL7490873 | 0.84 | GABRA1 (0.60) | GABRA1GABRA6GABRB2GABRA3GABRG2 | |
| SCHEMBL10656205 | 0.84 | GABRA1 (0.73) | GABRA1GABRA6GABRB2GABRA3GABRG2 | |
| SCHEMBL7487639 | 0.84 | GABRA1 (0.67) | GABRA1GABRA6GABRB2GABRA3 | |
| SCHEMBL10680370 | 0.83 | GABRA1 (0.58) | GABRA1GABRA6GABRB2GABRA3GABRG2 | |
| SCHEMBL10675841 | 0.82 | GABRA1 (0.58) | GABRA1GABRA6GABRB2GABRA3GABRG2 | |
| SCHEMBL10365933 | 0.80 | GABRA1 (0.55) | GABRA1GABRA6GABRA3GABRG2GABRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0241682-B1 | NOVEL BENZODIAZEPINE DERIVATIVES AND THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 1990-11-28 | — | — | EP | disclosed |
| US-4772599-A | ANTICONVULSANTS, ANXIOLYTICS, HYPNOTICS, NOOTROPICS | A/S FERROSAN (DK) | 1988-09-20 | — | — | US | disclosed |