Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.80 |
| ▸ | TSHR | P16473 | 2/20 | 0.80 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.80 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.66 |
| ▸ | RECQL | P46063 | 1/20 | 0.66 |
| ▸ | HTT | P42858 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.54 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.54 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.54 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.54 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.54 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2372546 | 0.98 | ALDH1A1 (0.83) | ALDH1A1TSHRCYP3A4SMN1; SMN2KDM4E | |
| Bicarbonate SCHEMBL11358602 | 0.91 | ALDH1A1 (0.82) | ALDH1A1TSHRCYP3A4SMN1; SMN2KDM4E | |
| SCHEMBL12819436 | 0.91 | ALDH1A1 (0.96) | ALDH1A1TSHRCYP3A4SMN1; SMN2KDM4E | |
| SCHEMBL13297951 | 0.91 | ALDH1A1 (0.90) | ALDH1A1TSHRCYP3A4SMN1; SMN2KDM4E | |
| SCHEMBL13812157 | 0.90 | ALDH1A1 (0.71) | ALDH1A1TSHRCYP3A4SMN1; SMN2KDM4E | |
| SCHEMBL6514053 | 0.90 | ALDH1A1 (0.71) | ALDH1A1TSHRCYP3A4SMN1; SMN2KDM4E | |
| SCHEMBL17205724 | 0.90 | ALDH1A1 (0.71) | ALDH1A1TSHRCYP3A4SMN1; SMN2KDM4E | |
| SCHEMBL29259787 | 0.89 | ALDH1A1 (1.00) | ALDH1A1TSHRCYP3A4SMN1; SMN2KDM4E | |
| SCHEMBL128274 | 0.89 | ALDH1A1 (1.00) | ALDH1A1TSHRCYP3A4SMN1; SMN2KDM4E | |
| SCHEMBL11361191 | 0.88 | ALDH1A1 (0.78) | ALDH1A1TSHRCYP3A4SMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0376870-A1 | A new organosilylpolyphosphoric reagent, its preparation and application to the process of synthesis of 3-carboxyquinolones or azaquinolones and their salts | CENTRO MARGA PARA LA INVESTIGACION S.A. (ES) | 1990-07-04 | — | — | EP | disclosed |