Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR1 | Q9Y271 | 8/20 | 0.46 |
| ▸ | GPBAR1 | Q8TDU6 | 4/20 | 0.46 |
| ▸ | CYSLTR2 | Q9NS75 | 3/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7509513 | 0.83 | CYSLTR1 (0.49) | CYSLTR1GPBAR1CYSLTR2ALOX5MAPT | |
| SCHEMBL8144813 | 0.83 | CYSLTR1 (0.66) | CYSLTR1GPBAR1CYSLTR2ALOX5SMN1; SMN2 | |
| SCHEMBL10669295 | 0.78 | CYSLTR1 (0.57) | CYSLTR1GPBAR1CYSLTR2SMN1; SMN2 | |
| SCHEMBL8108135 | 0.78 | CYSLTR1 (0.44) | CYSLTR1GPBAR1CYSLTR2 | |
| SCHEMBL10376026 | 0.78 | MAOB (0.53) | CYSLTR1GPBAR1CYSLTR2SMN1; SMN2 | |
| SCHEMBL1636426 | 0.76 | BCHE (0.58) | ALOX5 | |
| SCHEMBL3683256 | 0.76 | MAPT (0.51) | MAPTSMN1; SMN2 | |
| SCHEMBL10378235 | 0.76 | CYSLTR1 (0.69) | CYSLTR1GPBAR1 | |
| SCHEMBL10377943 | 0.75 | CYSLTR1 (0.43) | CYSLTR1GPBAR1CYSLTR2 | |
| SCHEMBL10377310 | 0.73 | CYSLTR1 (0.69) | CYSLTR1GPBAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4904786-A | Quinoline compounds as antiallergic and antiinflammatory agents | AMERICAN HOME PRODUCTS CORPORATION (US) | 1990-02-27 | — | — | US | disclosed |
| US-4772703-A | LIPOXYGENASE INHIBITORS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1988-09-20 | — | — | US | disclosed |