Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 5/20 | 0.64 |
| ▸ | ADRA2A | P08913 | 11/20 | 0.61 |
| ▸ | ADRA2B | P18089 | 10/20 | 0.61 |
| ▸ | ADRA2C | P18825 | 10/20 | 0.61 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.51 |
| ▸ | F12 | P00748 | 1/20 | 0.51 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.51 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.51 |
| ▸ | SNCA | P37840 | 1/20 | 0.48 |
| ▸ | F2 | P00734 | 1/20 | 0.47 |
| ▸ | C1R | P00736 | 1/20 | 0.47 |
| ▸ | F10 | P00742 | 1/20 | 0.47 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.47 |
| ▸ | KLK1 | P06870 | 1/20 | 0.47 |
| ▸ | GPR65 | Q8IYL9 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5803299 | 0.78 | PTGIR (1.00) | PTGIRADRA2AADRA2BADRA2C | |
| Trifluoroacetic Acid SCHEMBL3903056 | 0.77 | PTGIR (0.74) | PTGIRADRA2AADRA2BADRA2CPRSS1 | |
| SCHEMBL1643957 | 0.76 | MEN1 (0.56) | SNCA | |
| SCHEMBL25605204 | 0.76 | ADRA2A (0.75) | PTGIRADRA2AADRA2BADRA2CPRSS1 | |
| SCHEMBL8953899 | 0.76 | ADRA2A (0.79) | PTGIRADRA2AADRA2BADRA2C | |
| SCHEMBL7588328 | 0.75 | ADRA2A (0.64) | PTGIRADRA2AADRA2BADRA2CPRSS1 | |
| SCHEMBL27275424 | 0.74 | ADRA2A (0.77) | PTGIRADRA2AADRA2BADRA2CPRSS1 | |
| Hydrochloric Acid SCHEMBL7601691 | 0.74 | ADRA2A (0.77) | PTGIRADRA2AADRA2BADRA2C | |
| Hydrochloric Acid SCHEMBL3899129 | 0.74 | ADRA2A (0.77) | PTGIRADRA2AADRA2BADRA2C | |
| Hydrochloric Acid SCHEMBL7601687 | 0.73 | ADRA2A (0.75) | PTGIRADRA2AADRA2BADRA2CPRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0236646-B1 | ORTHO-ANISAMIDES, PROCESS FOR THEIR PREPARATION AND THEIR PHARMACEUTICAL APPLICATIONS | Laboratoires DELAGRANGE, Société Anonyme (FR) | 1990-10-10 | — | — | EP | claimed |