SCHEMBL10378404

SCHEMBL10378404

FC(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(Cl)Cl

nearest known ligand 0.41

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.41
TSHR P16473 1/20 0.41
TDP1 Q9NUW8 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10376221 0.94 KDM4E (0.46) KDM4ETSHRTDP1
SCHEMBL498059 0.83 KDM4E (0.43) KDM4ETSHRTDP1
SCHEMBL10376266 0.80 KDM4E (0.33) KDM4ETSHRTDP1
SCHEMBL5489726 0.79 TSHR (0.42) KDM4ETSHRTDP1
SCHEMBL1827978 0.79 TSHR (0.42) KDM4ETSHRTDP1
SCHEMBL5492824 0.79 TSHR (0.42) KDM4ETSHRTDP1
SCHEMBL1824498 0.79 TSHR (0.42) KDM4ETSHRTDP1
SCHEMBL1824897 0.79 TSHR (0.42) KDM4ETSHRTDP1
SCHEMBL5487202 0.79 TSHR (0.42) KDM4ETSHRTDP1
SCHEMBL1829371 0.79 TSHR (0.42) KDM4ETSHRTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1990010096-A1 A METHOD OF CLEANING USING HYDROCHLOROFLUOROCARBONS ALLIED-SIGNAL INC. (US) 1990-09-07 WO disclosed
US-4947881-A Method of cleaning using hydrochlorofluorocarbons ALLIED-SIGNAL INC. (US) 1990-08-14 US disclosed