Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
| ▸ | REN | P00797 | 1/20 | 0.31 |
| ▸ | AXL | P30530 | 1/20 | 0.31 |
| ▸ | MERTK | Q12866 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3950265 | 0.92 | REN (0.33) | REN | |
| SCHEMBL3950264 | 0.92 | REN (0.33) | REN | |
| SCHEMBL1040506 | 0.91 | AXL (0.38) | RENAXLMERTK | |
| SCHEMBL1040070 | 0.89 | REN (0.33) | BACE1RENAXLMERTK | |
| SCHEMBL2254105 | 0.87 | BACE1 (0.32) | BACE1RENAXLMERTK | |
| SCHEMBL2254103 | 0.87 | BACE1 (0.32) | BACE1RENAXLMERTK | |
| SCHEMBL1040426 | 0.86 | REN (0.35) | BACE1RENAXLMERTK | |
| SCHEMBL1498268 | 0.86 | REN (0.33) | BACE1RENAXLMERTK | |
| SCHEMBL1498266 | 0.86 | REN (0.33) | BACE1RENAXLMERTK | |
| SCHEMBL2252673 | 0.86 | REN (0.32) | BACE1RENAXLMERTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2049514-B1 | NITRATE ESTERS OF PIPERIDINES | NOVARTIS AG (CH) | 2011-01-26 | — | — | EP | disclosed |