⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21765685 | 0.97 | ALDH1A1 (0.54) | — | |
| SCHEMBL772021 | 0.97 | ATM (0.54) | — | |
| SCHEMBL20129907 | 0.94 | — | — | |
| SCHEMBL21765684 | 0.94 | ALDH1A1 (0.50) | — | |
| SCHEMBL27155224 | 0.88 | ALDH1A1 (0.62) | — | |
| SCHEMBL8149192 | 0.88 | ALDH1A1 (0.62) | — | |
| SCHEMBL2110436 | 0.79 | ALDH1A1 (0.52) | — | |
| SCHEMBL20985713 | 0.79 | ALDH1A1 (0.81) | — | |
| SCHEMBL11761315 | 0.79 | ATM (0.46) | — | |
| SCHEMBL21765680 | 0.78 | ALDH1A1 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 171 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250129077-A1 | SUBSTITUTED PURINES AS TLR7 AGONISTS | Primmune Therapeutics, Inc. | 2025-04-24 | — | — | US | disclosed |
| EP-4512816-A2 | TLR7 AGONISTS | Primmune Therapeutics, Inc. (US) | 2025-02-26 | — | — | EP | disclosed |
| CN-112533607-B | TLR7 agonists | 普利缪尼治疗学股份有限公司 | 2025-01-07 | — | — | CN | disclosed |
| CN-114423775-B | Aryl glucoside derivative, and preparation method and application thereof | 上海喆邺生物科技有限公司 | 2024-11-22 | — | — | CN | disclosed |
| US-20240376099-A1 | COMPOUNDS AND COMPOSITIONS AS INHIBITORS OF ENDOSOMAL TOLL-LIKE RECEPTORS | NOVARTIS AG (CH) | 2024-11-14 | — | — | US | disclosed |
| EP-3801538-B1 | TLR7 AGONISTS | PRIMMUNE THERAPEUTICS INC (US) | 2024-10-02 | — | — | EP | disclosed |
| WO-2024153595-A1 | CHROMANE DERIVATIVES AS EGFR SELECTIVE INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2024-07-25 | — | — | WO | disclosed |
| US-12037335-B2 | Substituted purines as TLR7 agonists | Primmune Therapeutics, Inc. (US) | 2024-07-16 | — | — | US | disclosed |
| WO-2024084447-A2 | AZETIDINYL BENZOXAZOLE COMPOUNDS AND THEIR USE AS MER AND AXL INHIBITORS | DONG-A ST CO., LTD. (KR) | 2024-04-25 | — | — | WO | disclosed |
| CN-117597329-A | Method for the catalytic synthesis of tryptamine and precursors thereof | 凯尔化学科技公司 | 2024-02-23 | — | — | CN | disclosed |
| WO-1993008175-A1 | BENZODIAZEPINE DERIVATIVES AS ANTAGONISTS OF GASTRIN AND/OR CHOLECYSTOKININ | GLAXO GROUP LIMITED (GB) | 1993-04-29 | — | — | WO | disclosed |
| EP-0538945-A1 | Benzodiazepine derivatives, and their use as antagonists of gastrin and/or cholecystokinin | GLAXO GROUP LIMITED (GB) | 1993-04-28 | — | — | EP | disclosed |
| US-5071869-A | 2-FLUOROCYCLOPROPYLACETIC ACID ESTERS, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS PESTICIDES | SCHERING AKTIENGESELLSCHAFT (DE) | 1991-12-10 | — | — | US | disclosed |
| US-5037976-A | Antimicrobial Agent | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1991-08-06 | — | — | US | disclosed |
| EP-0432861-A1 | Halogenated olefines, process for the preparation thereof and their use as pesticides | SCHERING AKTIENGESELLSCHAFT (DE) | 1991-06-19 | — | — | EP | disclosed |
| EP-0430380-A2 | 2-Fluorocyclopropylacetic acid esters, processes for their preparation and their use as pesticides | SCHERING AKTIENGESELLSCHAFT (DE) | 1991-06-05 | — | — | EP | disclosed |
| US-5019573-A | Substituted dibenzofurans and methods of using same | EUROCELTIQUE, S.A. (LU) | 1991-05-28 | — | — | US | disclosed |
| EP-0422329-A1 | Substituted dibenzofurans and methods of using same | Euro-Celtique S.A. (LU) | 1991-04-17 | — | — | EP | disclosed |
| US-4898859-A | 2-Oxa-isocephem compounds and compositions containing same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1990-02-06 | — | — | US | disclosed |
| EP-0282895-A2 | 2-oxa-isocephem compounds, compositions containing same and processes for preparing same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1988-09-21 | — | — | EP | disclosed |