Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 5/20 | 0.81 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.81 |
| ▸ | NPC1 | O15118 | 2/20 | 0.60 |
| ▸ | RAB9A | P51151 | 2/20 | 0.60 |
| ▸ | POLB | P06746 | 4/20 | 0.57 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | CA12 | O43570 | 1/20 | 0.54 |
| ▸ | CA1 | P00915 | 1/20 | 0.54 |
| ▸ | CA2 | P00918 | 1/20 | 0.54 |
| ▸ | CA9 | Q16790 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL96123 | 0.90 | HPGD (1.00) | HPGDALDH1A1NPC1RAB9APOLB | |
| SCHEMBL10517748 | 0.90 | HPGD (1.00) | HPGDALDH1A1NPC1RAB9APOLB | |
| Sulfuric Acid SCHEMBL28756598 | 0.87 | HPGD (0.79) | HPGDALDH1A1NPC1RAB9APOLB | |
| Butanedione SCHEMBL28072236 | 0.86 | HPGD (0.92) | HPGDALDH1A1NPC1RAB9APOLB | |
| Acetic Acid SCHEMBL28756539 | 0.86 | HPGD (0.92) | HPGDALDH1A1NPC1RAB9APOLB | |
| SCHEMBL28472793 | 0.79 | HPGD (0.78) | HPGDALDH1A1NPC1RAB9APOLB | |
| SCHEMBL29521664 | 0.78 | POLB (0.75) | HPGDALDH1A1NPC1RAB9APOLB | |
| SCHEMBL81434 | 0.78 | POLB (0.75) | HPGDALDH1A1NPC1RAB9APOLB | |
| SCHEMBL31309573 | 0.78 | CA1 (0.70) | HPGDALDH1A1CA12CA1CA2 | |
| SCHEMBL4463532 | 0.78 | CA1 (0.70) | HPGDALDH1A1CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1990015600-A2 | TREATMENT OF CHRONIC INFLAMMATORY JOINT DISEASE WITH ARYLSULFONAMIDES | A.H. ROBINS COMPANY, INCORPORATED (US) | 1990-12-27 | — | — | WO | disclosed |