SCHEMBL81434

SCHEMBL81434

Cc1ccccc1NC(N)=O

nearest known ligand 0.75

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.75
NPC1 O15118 2/20 0.72
RAB9A P51151 2/20 0.72
HPGD P15428 6/20 0.69
ALDH1A1 P00352 3/20 0.69
MAPK1 P28482 2/20 0.61
HSD17B10 Q99714 2/20 0.61
MAPT P10636 1/20 0.61
ALOX12 P18054 1/20 0.58
HTT P42858 2/20 0.56
GRIN2D O15399 2/20 0.56
GRIN3B O60391 2/20 0.56
GRIN1 Q05586 2/20 0.56
GRIN2A Q12879 2/20 0.56
GRIN2B Q13224 2/20 0.56
GRIN2C Q14957 2/20 0.56
GRIN3A Q8TCU5 2/20 0.56
SIGMAR1 Q99720 2/20 0.56
KDM4E B2RXH2 2/20 0.56
EPHX1 P07099 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29521664 1.00 POLB (0.75) POLBNPC1RAB9AHPGDALDH1A1
Hydrochloric Acid SCHEMBL27918048 0.98 POLB (0.72) POLBNPC1RAB9AHPGDALDH1A1
Phosphine SCHEMBL30387635 0.98 POLB (0.72) POLBNPC1RAB9AHPGDALDH1A1
Carbamic Acid SCHEMBL11482904 0.87 RAB9A (0.67) POLBNPC1RAB9AHPGDALDH1A1
SCHEMBL1272314 0.86 POLB (1.00) POLBNPC1RAB9AHPGDALDH1A1
SCHEMBL25356036 0.85 NPC1 (0.77) POLBNPC1RAB9AHPGDALDH1A1
SCHEMBL29892467 0.85 MAPT (0.61) POLBNPC1RAB9AALDH1A1HSD17B10
SCHEMBL1140606 0.85 MAPT (0.61) POLBNPC1RAB9AALDH1A1HSD17B10
SCHEMBL29840068 0.85 GAA (0.67) POLBNPC1RAB9AHPGDALDH1A1
SCHEMBL3928666 0.85 GAA (0.67) POLBNPC1RAB9AHPGDALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 417 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250297039-A1 OLEFIN POLYMERIZATION CATALYST COMPONENTS CONTAINING DIGLYCIDYLESTER COMPONENTS AND ITS USE FOR THE PRODUCTION OF POLYPROPYLENE HAVING HIGH ISOTACTICITY AT HIGH MELT FLOW RATE FORMOSA PLASTICS CORP USA (US) 2025-09-25 US claimed
CN-113906321-B Polarizing plate, method for manufacturing same, and image display device 住友化学株式会社 2024-10-15 CN claimed
US-20240262801-A1 COMPOUNDS HAVING 5-(2-FLUORO-6-HYDROXYPHENYL)-1,2,5-THIADIAZOLIDIN-3-ONE 1,1-DIOXIDE AS INHIBITORS OF PROTEIN KINASE PHOSPHATASE ENZYMES MONDEGO BIO, LDA. (PT) 2024-08-08 US claimed
CN-117617257-A Fungicidal compositions and methods of using the same 江苏中旗科技股份有限公司 2024-03-01 CN claimed
CN-115583989-B SSTR 2-targeted compound and preparation method and application thereof 烟台蓝纳成生物技术有限公司 2023-02-28 CN claimed
CN-115583989-A SSTR 2-targeted compound and preparation method and application thereof 烟台蓝纳成生物技术有限公司 2023-01-10 CN claimed
CN-112250661-B Method for catalytically synthesizing lactide 南京大学 2021-11-02 CN claimed
CN-112250661-A Method for catalytically synthesizing lactide 南京大学 2021-01-22 CN claimed
CN-111826151-A Dialkyl urea type supermolecule thickening agent and preparation method and application thereof 中国石油大学(华东) 2020-10-27 CN claimed
CN-109414420-A The inhibitor and its application method of indole amine 2,3-dioxygenase 百时美施贵宝公司 2019-03-01 CN claimed
US-20060281725-A1 Agents and crystals for improving excretory potency of urinary bladder ISIHARA YUJI 2006-12-14 US claimed
CN-1850793-A Water phase high pressure method for preparing N,N'-di (m-tolyl) urea UNIV ZHEJIANG (CN) 2006-10-25 CN claimed
EP-1604653-A1 Acetylcholinesterase inhibitors for improving excretory potency of urinary bladder Takeda Pharmaceutical Company Limited (JP) 2005-12-14 EP claimed
US-20040116457-A1 Agents for improving excretory potency of urinary bladder TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2004-06-17 US claimed
US-20020177593-A1 Agents and crystals for improving excretory potency of urinary bladder TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2002-11-28 US claimed
EP-1118322-A1 DRUGS FOR IMPROVING VESICAL EXCRETORY STRENGTH Takeda Chemical Industries, Ltd. (JP) 2001-07-25 EP claimed
CN-1283181-A Substituted beta-alanines AWONGTISFAMA CO LTD (GB) 2001-02-07 CN claimed
CN-1265672-A Sulphonylated dipeptide Compounds capable of inhibiting leukocyte adhesion mediated by VLA-4 ELAND PHARMACEUTICALS CO (US) 2000-09-06 CN claimed
EP-1005459-A1 SUBSTITUTED ISOQUINOLINES AS ANTICONVULSIVANTS SMITHKLINE BEECHAM PLC (GB) 2000-06-07 EP claimed
WO-1999014197-A1 SUBSTITUTED ISOQUINOLINES AS ANTICONVULSIVANTS SMITHKLINE BEECHAM PLC (GB) 1999-03-25 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240262801-A1 COMPOUNDS HAVING 5-(2-FLUORO-6-HYDROXYPHENYL)-1,2,5-THIADIAZOLIDIN-3-ONE 1,1-DIOXIDE AS INHIBITORS OF PROTEIN KINASE PHOSPHATASE ENZYMES PPM1A, TH, PPM1G POLB 1935/4885NPC1 2925/4885RAB9A 2110/4885
US-20020177593-A1 Agents and crystals for improving excretory potency of urinary bladder ACHE, BPHL, BCHE POLB 2405/4885NPC1 1932/4885RAB9A 1071/4885
US-20060281725-A1 Agents and crystals for improving excretory potency of urinary bladder ACHE, BCHE, PDE7A POLB 1689/4885NPC1 2214/4885RAB9A 812/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.