Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.52 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | STAT3 | P40763 | 1/20 | 0.50 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.50 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.50 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.50 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9837640 | 0.89 | SMN1; SMN2 (0.67) | KMT2ASMN1; SMN2MEN1MAPK1HIF1A | |
| SCHEMBL28069120 | 0.87 | KDM4E (0.59) | KMT2AEPHX2SMN1; SMN2LMNAMAPT | |
| SCHEMBL65840 | 0.80 | SMN1; SMN2 (0.62) | KMT2ASMN1; SMN2MEN1MAPK1LMNA | |
| SCHEMBL9086875 | 0.80 | EPHX2 (0.52) | KMT2AEPHX2SMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL10380234 | 0.79 | BTK (0.60) | KMT2ASMN1; SMN2MEN1MAPK1MAPT | |
| SCHEMBL11926736 | 0.77 | KDM4E (0.65) | EPHX2SMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL12858056 | 0.76 | ALDH1A1 (0.59) | KMT2ALMNAMAPTALDH1A1KDM4E | |
| SCHEMBL9837917 | 0.75 | KMT2A (0.68) | KMT2ASMN1; SMN2MEN1MAPTALDH1A1 | |
| SCHEMBL14100178 | 0.75 | EPHX2 (0.50) | EPHX2SMN1; SMN2LMNAMAPTALDH1A1 | |
| SCHEMBL4121972 | 0.75 | KMT2A (0.72) | KMT2ASMN1; SMN2MEN1MAPK1HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1990008128-A1 | NOVEL PRODRUG DERIVATIVES OF BIOLOGICALLY ACTIVE AGENTS CONTAINING HYDROXYL GROUPS OR NH-ACIDIC GROUPS | BUNDGAARD HANS (DK) | 1990-07-26 | — | — | WO | disclosed |