Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | TNKS | O95271 | 2/20 | 0.36 |
| ▸ | TNKS2 | Q9H2K2 | 2/20 | 0.36 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.35 |
| ▸ | PDE5A | O76074 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1343569 | 1.00 | PARP1 (0.40) | PARP1KDM4ERECQLALDH1A1MAPT | |
| SCHEMBL1544255 | 1.00 | PARP1 (0.40) | PARP1KDM4ERECQLALDH1A1MAPT | |
| SCHEMBL989212 | 0.89 | MAPT (0.38) | PARP1KDM4EALDH1A1MAPTMEN1 | |
| SCHEMBL989215 | 0.89 | MAPT (0.38) | PARP1KDM4EALDH1A1MAPTMEN1 | |
| SCHEMBL987844 | 0.89 | PARP1 (0.39) | PARP1KDM4ERECQLALDH1A1MAPT | |
| SCHEMBL987842 | 0.89 | PARP1 (0.39) | PARP1KDM4ERECQLALDH1A1MAPT | |
| SCHEMBL3674775 | 0.89 | KDM4E (0.43) | PARP1KDM4ERECQLALDH1A1MAPT | |
| SCHEMBL3674777 | 0.89 | KDM4E (0.43) | PARP1KDM4ERECQLALDH1A1MAPT | |
| SCHEMBL2320352 | 0.88 | PARP1 (0.42) | PARP1KDM4ERECQLALDH1A1MAPT | |
| SCHEMBL2320356 | 0.88 | PARP1 (0.42) | PARP1KDM4ERECQLALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7863284-B2 | Anti-cancer cyclopenta[G]quinazoline compounds | BTG INTERNATIONAL LIMITED (GB) | 2011-01-04 | — | — | US | disclosed |