Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.36 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | DRD1 | P21728 | 1/20 | 0.36 |
| ▸ | HRH2 | P25021 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | SCN1A | P35498 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL217733 | 0.84 | PPM1B (0.34) | PPM1BPTPN1PPP1CC | |
| SCHEMBL11600880 | 0.78 | ALDH1A1 (0.33) | MAPTNPSR1PPM1BPTPN1PPP1CC | |
| SCHEMBL11858353 | 0.77 | CYP3A4 (0.54) | MAPTCYP3A4ABCB11LMNACYP1A2 | |
| SCHEMBL28443625 | 0.74 | CYP3A4 (0.40) | MAPTCYP3A4ABCB11LMNACYP1A2 | |
| SCHEMBL28443626 | 0.74 | CYP3A4 (0.40) | MAPTCYP3A4ABCB11LMNACYP1A2 | |
| SCHEMBL20103712 | 0.73 | CYP3A4 (0.50) | MAPTCYP3A4ABCB11LMNACYP1A2 | |
| SCHEMBL20054732 | 0.73 | CYP3A4 (0.50) | MAPTCYP3A4ABCB11LMNACYP1A2 | |
| SCHEMBL27759738 | 0.73 | MAPT (0.36) | MAPTCYP3A4ABCB11LMNACYP1A2 | |
| SCHEMBL1709532 | 0.73 | CYP3A4 (0.45) | MAPTCYP3A4ABCB11LMNACYP1A2 | |
| SCHEMBL3669479 | 0.72 | NPSR1 (0.39) | MAPTCYP3A4ABCB11LMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4957960-A | FOR ELECTRONIC DEVICES; CURABLE SILICONE RESIN AND AS AN ION SCAVENGER COMPOUND A CALIXARENE OR OXACALIXARENE COMPOUND, A SILACROWN OR POLYALKYLENE ETHER DERIVATIVE | LOCTITE (IRELAND) LTD. (IE) | 1990-09-18 | — | — | US | disclosed |
| US-4908399-A | Curable epoxy resin, metal ion scavenger comprising calixarene derivatives, silacrowns, polyalkylene ether derivatives | LOCTITE (IRELAND) LTD. (IE) | 1990-03-13 | — | — | US | disclosed |
| WO-1988002386-A1 | ENCAPSULATING COMPOSITIONS | LOCTITE CORPORATION (US) | 1988-04-07 | — | — | WO | disclosed |
| EP-0262910-A2 | Encapsulating compositions | LOCTITE (IRELAND) Ltd. (IE) | 1988-04-06 | — | — | EP | disclosed |