Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | CCR2 | P41597 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL217734 | 0.84 | — | — | |
| SCHEMBL3958198 | 0.80 | PPM1B (0.30) | — | |
| SCHEMBL679493 | 0.77 | — | — | |
| SCHEMBL27660738 | 0.77 | CYP2C19 (0.49) | CHRM3CCR2MAPTCYP2C19 | |
| SCHEMBL23607775 | 0.75 | — | — | |
| SCHEMBL15384219 | 0.75 | CYP2C19 (0.46) | CHRM3CCR2MAPTCYP2C19 | |
| SCHEMBL3669481 | 0.74 | FFAR3 (0.42) | CHRM3MAPTCYP2C19 | |
| SCHEMBL4179061 | 0.73 | CHRM2 (0.40) | CHRM3MEN1KMT2A | |
| SCHEMBL464840 | 0.73 | CYP2C19 (0.36) | CHRM3MAPTCYP2C19 | |
| SCHEMBL2914633 | 0.73 | TFPI2 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4957960-A | FOR ELECTRONIC DEVICES; CURABLE SILICONE RESIN AND AS AN ION SCAVENGER COMPOUND A CALIXARENE OR OXACALIXARENE COMPOUND, A SILACROWN OR POLYALKYLENE ETHER DERIVATIVE | LOCTITE (IRELAND) LTD. (IE) | 1990-09-18 | — | — | US | disclosed |
| US-4908399-A | Curable epoxy resin, metal ion scavenger comprising calixarene derivatives, silacrowns, polyalkylene ether derivatives | LOCTITE (IRELAND) LTD. (IE) | 1990-03-13 | — | — | US | disclosed |
| WO-1988002386-A1 | ENCAPSULATING COMPOSITIONS | LOCTITE CORPORATION (US) | 1988-04-07 | — | — | WO | disclosed |
| EP-0262910-A2 | Encapsulating compositions | LOCTITE (IRELAND) Ltd. (IE) | 1988-04-06 | — | — | EP | disclosed |