Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3019715 | 0.92 | LMNA (0.34) | TSHRSMN1; SMN2DNM1 | |
| SCHEMBL3019713 | 0.92 | LMNA (0.34) | TSHRSMN1; SMN2DNM1 | |
| SCHEMBL12475219 | 0.89 | TSHR (0.48) | TSHRSMN1; SMN2DNM1 | |
| Ammonia Solution, Strong SCHEMBL28575731 | 0.86 | TSHR (0.46) | TSHRSMN1; SMN2DNM1 | |
| SCHEMBL12475735 | 0.84 | TSHR (0.44) | TSHRSMN1; SMN2DNM1 | |
| Hydrochloric Acid SCHEMBL28463630 | 0.84 | TSHR (0.44) | TSHRSMN1; SMN2DNM1 | |
| SCHEMBL5294434 | 0.83 | — | — | |
| SCHEMBL8755967 | 0.81 | TSHR (0.41) | TSHRSMN1; SMN2DNM1 | |
| SCHEMBL10467297 | 0.81 | TSHR (0.41) | TSHRSMN1; SMN2DNM1 | |
| SCHEMBL4797106 | 0.79 | TSHR (0.56) | TSHRSMN1; SMN2DNM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0174956-B1 | SOFT $g(b)-ADRENERGIC BLOCKING AGENTS | BODOR, Nicholas S. (US) | 1990-08-16 | — | — | EP | disclosed |