Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 3/20 | 0.33 |
| ▸ | EDNRB | P24530 | 2/20 | 0.33 |
| ▸ | EDNRA | P25101 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | GRM5 | P41594 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | PPARA | Q07869 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1038957 | 0.91 | REN (0.33) | RENBACE1 | |
| SCHEMBL1040349 | 0.89 | REN (0.35) | RENTHRBTP53MAPTALDH1A1 | |
| SCHEMBL1036571 | 0.88 | MAPT (0.41) | RENTHRBTP53MAPTALDH1A1 | |
| SCHEMBL1038578 | 0.88 | REN (0.37) | RENTHRBTP53MAPTALDH1A1 | |
| SCHEMBL1040647 | 0.88 | REN (0.37) | RENTHRBTP53MAPTALDH1A1 | |
| SCHEMBL1040648 | 0.88 | REN (0.37) | RENTHRBTP53MAPTALDH1A1 | |
| SCHEMBL1038580 | 0.88 | REN (0.37) | RENTHRBTP53MAPTALDH1A1 | |
| SCHEMBL3905401 | 0.87 | REN (0.36) | RENTHRBTP53MAPTALDH1A1 | |
| SCHEMBL1040580 | 0.87 | REN (0.36) | RENTHRBTP53MAPTALDH1A1 | |
| SCHEMBL1040582 | 0.87 | REN (0.36) | RENTHRBTP53MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2049514-B1 | NITRATE ESTERS OF PIPERIDINES | NOVARTIS AG (CH) | 2011-01-26 | — | — | EP | disclosed |