Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL10383894

C=CC(=O)Nc1ccc(S(=O)(=O)O)cc1.N

nearest known ligand 0.70

Full drug profile on Sugi Atlas →

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TGM2 P21980 19/20 0.70
F13A1 P00488 10/20 0.63
TGM1 P22735 10/20 0.63
LMNA P02545 1/20 0.58
TGM3 Q08188 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1815668 0.98 TGM2 (0.72) TGM2F13A1TGM1LMNATGM3
SCHEMBL3893222 0.96 TGM2 (0.70) TGM2F13A1TGM1LMNATGM3
SCHEMBL28673029 0.89 TGM2 (0.60) TGM2F13A1TGM1LMNATGM3
SCHEMBL439369 0.82 TGM2 (0.79) TGM2F13A1TGM1LMNATGM3
SCHEMBL28576027 0.82 TGM2 (0.70) TGM2F13A1TGM1LMNATGM3
SCHEMBL202328 0.82 TGM2 (0.70) TGM2F13A1TGM1LMNATGM3
SCHEMBL10405297 0.82 TGM2 (1.00) TGM2F13A1TGM1LMNATGM3
SCHEMBL10872341 0.80 TGM2 (0.53) TGM2F13A1TGM1LMNATGM3
SCHEMBL27806115 0.80 TGM2 (0.62) TGM2F13A1TGM1LMNATGM3
SCHEMBL7894169 0.79 TGM2 (0.66) TGM2F13A1TGM1LMNATGM3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4959432-A HEAT RESISTANCE UNION CARBIDE CHEMICALS AND PLASTICS COMPANY INC. (US) 1990-09-25 US disclosed
US-4889887-A CROSSLINKED N-(ALKOXYMETHYLENE)ACRYLYL COMPOUNDS UNION CARBIDE CHEMICALS AND PLASTICS COMPANY INC. (US) 1989-12-26 US disclosed