Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.37 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.37 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.37 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CDK1 | P06493 | 1/20 | 0.36 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.36 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.36 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.36 |
| ▸ | ALPL | P05186 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10915190 | 0.94 | MAPT (0.42) | MAPTKDM4EALDH1A1NPC1GAA | |
| SCHEMBL10695682 | 0.91 | MAPT (0.46) | MAPTKDM4EALDH1A1NPC1GAA | |
| SCHEMBL10383235 | 0.88 | GAA (0.58) | MAPTKDM4EALDH1A1NPC1GAA | |
| SCHEMBL10913796 | 0.86 | ALDH1A1 (0.46) | MAPTKDM4EALDH1A1NPC1GAA | |
| SCHEMBL10692208 | 0.85 | MAPT (0.43) | MAPTKDM4EALDH1A1NPC1GAA | |
| SCHEMBL10916479 | 0.85 | GAA (0.52) | MAPTALDH1A1GAACDK1SMN1; SMN2 | |
| SCHEMBL7805854 | 0.84 | MAPT (0.42) | MAPTKDM4EALDH1A1NPC1GAA | |
| SCHEMBL11000660 | 0.83 | MAPT (0.42) | MAPTKDM4EALDH1A1NPC1GAA | |
| SCHEMBL11175919 | 0.83 | MAPT (0.46) | MAPTKDM4EALDH1A1NPC1GAA | |
| SCHEMBL10889026 | 0.82 | ALDH1A1 (0.50) | MAPTKDM4EALDH1A1NPC1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0122231-B1 | HERBICIDAL AGENT | CIBA-GEIGY AG (CH) | 1990-01-17 | — | — | EP | claimed |
| EP-0044808-B1 | N-PHENYLSULFONYL-N'-PYRIMIDINYL- AND -TRIAZINYL UREAS | CIBA-GEIGY AG (CH) | 1986-01-15 | — | — | EP | claimed |
| US-4537619-A | HERBICIDES AND PLANT GROWTH REGULATORS | CIBA GEIGY CORPORATION (US) | 1985-08-27 | — | — | US | claimed |
| US-4911751-A | Using a sulfonylurea heterocyclic compound | CIBA-GEIGY CORPORATION (US) | 1990-03-27 | — | — | US | disclosed |
| US-4537619-A | HERBICIDES AND PLANT GROWTH REGULATORS | CIBA GEIGY CORPORATION (US) | 1985-08-27 | — | — | US | disclosed |